Association of peripheral blood-derived mesenchymal stem cells exosomal circular RNAs with diagnosis and inflammatory response in acute mesenteric ischemia

Table 1 Baseline data

Variables	AMI group (n = 80)	Control group (n = 125)	P value
Gender (male/female)	51/29	88/37	0.320
Age	62.850 ± 6.963	52.590 ± 10.798	< 0.001
BMI	28.530 ± 4.927	22.280 ± 1.604	< 0.001
Cardiovascular history
Arterial hypertension	37	44	0.114
Atrial fibrillation	26	8	< 0.001
Coronary heart disease	14	19	0.662
Cerebral infarction	20	20	0.113
Clinical symptoms
Vomiting	36	53	0.714
Diarrhea	16	26	0.890
Hematochezia	28	37	0.418

AMI: Acute mesenteric ischemia; BMI: Body mass index.

Table 2 Acute mesenteric ischemia subgroups

Variables	AMI patients (n = 80)
Cause of vascular insufficiency
Arterial stenosis	16
Arterial thrombosis	22
Arterial embolus	10
Mesenteric vein thrombosis	9
Portal vein thrombosis	7
Mesenteric vein compression	6
Portal vein compression	10
Stage
Early AMI	36
Necrotic AMI	44

AMI: Acute mesenteric ischemia.

Table 3 Preoperative biochemical and inflammatory variables

Variables	AMI group (n = 80)	Control group (n = 125)	P value
Biochemical variables
Neutrophils count (× 109)	8.480 ± 5.346	7.692 ± 6.603	0.408
Platelets count (× 109)	264 ± 42	221 ± 23	0.395
Lymphocytes count (× 109)	1.302 ± 2.944	1.024 ± 3.750	0.502
NLR	10.124 ± 2.724	6.086 ± 1.702	< 0.001
PLR	195.537 ± 169.450	178.056 ± 153.799	0.466
IFABP, pg/mL	615.762 ± 348.743	447.806 ± 185.106	< 0.001
D-lactate, nmol/mL	446.387 ± 129.760	274.089 ± 97.689	< 0.001
Inflammatory variables
IL-6, pg/mL	24.5585 ± 18.742	4.876 ± 4.332	< 0.001
TNF-α, pg/mL	86.630 ± 82.076	70.258 ± 56.476	0.118

AMI: Acute mesenteric ischemia; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; IFABP: Intestinal fatty acid binding protein; IL: Interleukin; TNF: Tumor necrosis factor.