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Contents Volume 17 Issue 5 May 26, 2025

Editorial

Are mesenchymal stem/stromal cells a novel avenue for the treatment of non-alcoholic fatty liver disease?

Milton Artur Ruiz, Roberto Luiz R Kaiser Junior, Gabriel Piron-Ruiz, Luiz Gustavo de Quadros

World J Stem Cells 17(5):99638. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.99638

Abstract (319) | Core Tip (308) | Full Article (HTML) (1146) | Full Article (PDF)-394K (84) | Full Article with Cover (PDF)-705K (110) | Full Article (XML)-77K (63) | Audio-142K (11) | Peer-Review Report-200K (69) | Answering Reviewers-72K (61) | Received: 07/26/2024 | Revised: 12/27/2024 | Accepted: 04/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (3103) | Similar Articles (227) | Timeline of Article Publication (3) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Aberrant bone formation and dysregulated bone homeostasis in ankylosing spondylitis

Gun Woo Lee

World J Stem Cells 17(5):106934. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.106934

Abstract (297) | Core Tip (337) | Full Article (HTML) (906) | Tables (1-1) (273) | Full Article (PDF)-374K (115) | Full Article with Cover (PDF)-687K (85) | Full Article (XML)-49K (76) | Audio-426K (16) | Peer-Review Report-215K (104) | Answering Reviewers-78K (108) | Received: 03/10/2025 | Revised: 04/03/2025 | Accepted: 05/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3346) | Similar Articles (16) | Timeline of Article Publication (3) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Review

Circular RNAs inducing the osteogenic differentiation of dental mesenchymal stem cells via microRNA sponging

Yong-Song Jiang, Wei-Sheng Wei, Dao-Tao Xie, Gang Guo

World J Stem Cells 17(5):101638. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.101638

Abstract (312) | Core Tip (311) | Full Article (HTML) (967) | Figures (1-1) (247) | Tables (1-1) (250) | Full Article (PDF)-766K (89) | Full Article with Cover (PDF)-1077K (111) | Full Article (XML)-263K (62) | Audio-7659K (11) | Peer-Review Report-173K (71) | Answering Reviewers-97K (94) | Received: 09/21/2024 | Revised: 11/24/2024 | Accepted: 04/14/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3415) | Similar Articles (52) | Timeline of Article Publication (4) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Stem cell therapy for retinal pigment epithelium disorders

Francesco Saverio Sorrentino, Francesco Parmeggiani, Lorenzo Gardini, Luigi Fontana, Mutali Musa, Caterina Gagliano, Marco Zeppieri

World J Stem Cells 17(5):103100. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.103100

Abstract (317) | Core Tip (371) | Full Article (HTML) (2685) | Figures (1-2) (357) | Full Article (PDF)-1143K (160) | Full Article with Cover (PDF)-1451K (106) | Full Article (XML)-220K (61) | Audio-349K (12) | Peer-Review Report-264K (63) | Answering Reviewers-602K (63) | Received: 11/07/2024 | Revised: 02/17/2025 | Accepted: 04/16/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4949) | Similar Articles (28) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Reader Comments (1) | What about the content of this article? (0) | Cite |

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Quality by design strategy of human mesenchymal stem/stromal cell drug products for the treatment of knee osteoarthritis

Hao Yu, Fan Zhang, Yi-Chen He, Lei-Sheng Zhang

World J Stem Cells 17(5):106547. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.106547

Abstract (315) | Core Tip (320) | Full Article (HTML) (1315) | Figures (1-2) (260) | Tables (1-1) (291) | Full Article (PDF)-1945K (121) | Full Article with Cover (PDF)-2255K (101) | Full Article (XML)-201K (82) | Audio-1214K (20) | Peer-Review Report-226K (66) | Answering Reviewers-231K (56) | Received: 02/28/2025 | Revised: 04/01/2025 | Accepted: 05/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4557) | Similar Articles (22) | Timeline of Article Publication (6) | Authors Evaluation (5) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Minireviews

Effect of adipokines on bone marrow mesenchymal stem cell function

Rui-Ming Wen, Hai-Xia Wang

World J Stem Cells 17(5):106150. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.106150

Abstract (329) | Core Tip (289) | Full Article (HTML) (1401) | Figures (1-2) (257) | Tables (1-1) (255) | Full Article (PDF)-2293K (85) | Full Article with Cover (PDF)-2603K (82) | Full Article (XML)-208K (59) | Audio-156K (8) | Peer-Review Report-269K (51) | Answering Reviewers-116K (64) | Received: 02/21/2025 | Revised: 03/23/2025 | Accepted: 04/09/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3726) | Similar Articles (0) | Timeline of Article Publication (7) | Authors Evaluation (6) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Clinical Trials Study

Multiroute administration of Wharton’s jelly mesenchymal stem cells in chronic complete spinal cord injury: A phase I safety and feasibility study

Necati Kaplan, Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Tolga Akkoc, Osman Boyalı, Erek Öztürk, Halil Can, Ali Genc, Erdal Karaöz

World J Stem Cells 17(5):101675. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.101675

Abstract (320) | Core Tip (367) | Full Article (HTML) (1239) | Figures (1-6) (308) | Tables (1-13) (268) | Full Article (PDF)-3961K (120) | Full Article with Cover (PDF)-4267K (124) | Full Article (XML)-166K (67) | Audio-695K (62) | Peer-Review Report-248K (67) | Answering Reviewers-777K (74) | Received: 09/26/2024 | Revised: 01/09/2025 | Accepted: 03/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (4562) | Similar Articles (48) | Timeline of Article Publication (3) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Basic Study

Collagen III combined with autologous adipose-derived mesenchymal stem cells accelerates burn wound healing in a rat model

Xiao-Long Zhou, Ben Wu, Zi-Jing Xie, Hong-De Li

World J Stem Cells 17(5):101898. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.101898

Abstract (332) | Core Tip (293) | Full Article (HTML) (926) | Figures (1-4) (294) | Full Article (PDF)-14700K (85) | Full Article with Cover (PDF)-15012K (90) | Full Article (XML)-59K (61) | Audio-1557K (15) | Peer-Review Report-189K (56) | Answering Reviewers-894K (49) | Received: 09/30/2024 | Revised: 12/31/2024 | Accepted: 04/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4324) | Similar Articles (10) | Timeline of Article Publication (5) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Optimal good manufacturing practice-compliant production of dental follicle stem cell sheet and its application in Sprague-Dawley rat periodontitis

Jia-Lu Yu, Chao Yang, Li Liu, An Lin, Shu-Juan Guo, Wei-Dong Tian

World J Stem Cells 17(5):104116. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.104116

Abstract (296) | Core Tip (314) | Full Article (HTML) (1298) | Figures (1-6) (274) | Full Article (PDF)-31777K (135) | Full Article with Cover (PDF)-32086K (97) | Full Article (XML)-177K (63) | Audio-2598K (19) | Peer-Review Report-276K (57) | Answering Reviewers-1918K (97) | Supplementary Material-231K (62) | Received: 12/10/2024 | Revised: 02/27/2025 | Accepted: 04/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (4999) | Similar Articles (21) | Timeline of Article Publication (3) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease

Ke-Bing Zhou, Li Nie, Mei-Li Wang, Dong-Hua Xiao, Hai-Yan Zhang, Xia Yang, Duan-Fang Liao, Xue-Feng Yang

World J Stem Cells 17(5):105266. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.105266

Abstract (313) | Core Tip (305) | Full Article (HTML) (951) | Figures (1-7) (295) | Tables (1-1) (278) | Full Article (PDF)-15893K (91) | Full Article with Cover (PDF)-16205K (87) | Full Article (XML)-108K (57) | Audio-1454K (10) | Peer-Review Report-180K (55) | Answering Reviewers-233K (76) | Supplementary Material-520K (65) | Received: 02/11/2025 | Revised: 03/17/2025 | Accepted: 05/09/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3948) | Similar Articles (29) | Timeline of Article Publication (5) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Cell-free extracts from human fat tissue attenuate ischemic injury in cardiomyocytes in a murine model

Tian-Yun Yang, Yi Sun, Wen-Jie Zhang, Chang-Qian Wang, Jin Zhou

World J Stem Cells 17(5):105394. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.105394

Abstract (302) | Core Tip (296) | Full Article (HTML) (665) | Figures (1-6) (291) | Full Article (PDF)-6640K (84) | Full Article with Cover (PDF)-6951K (89) | Full Article (XML)-99K (71) | Audio-1298K (25) | Peer-Review Report-245K (69) | Answering Reviewers-135K (64) | Received: 01/20/2025 | Revised: 02/27/2025 | Accepted: 04/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3846) | Similar Articles (69) | Timeline of Article Publication (4) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Letter to the Editor

Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia

Ramya Lakshmi Rajendran, Byeong-Cheol Ahn, Prakash Gangadaran

World J Stem Cells 17(5):107078. Published online May 26, 2025. doi: 10.4252/wjsc.v17.i5.107078

Abstract (313) | Core Tip (342) | Full Article (HTML) (4626) | Full Article (PDF)-348K (191) | Full Article with Cover (PDF)-661K (78) | Full Article (XML)-26K (54) | Audio-272K (14) | Peer-Review Report-184K (59) | Answering Reviewers-101K (59) | Received: 03/14/2025 | Revised: 04/03/2025 | Accepted: 05/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (7535) | Similar Articles (8) | Timeline of Article Publication (4) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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