Innovations in the treatment of endometrial diseases: Role of human umbilical cord mesenchymal stem cells and their exosomes

doi:10.4252/wjsc.v18.i5.115486

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. May 26, 2026; 18(5): 115486
Published online May 26, 2026. doi: 10.4252/wjsc.v18.i5.115486

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Figure 1 Schematic figure illustrating the mechanisms of human umbilical cord mesenchymal stem cells and their exosomes in the treatment of endometrial diseases. HUC-MSCs: Human umbilical cord mesenchymal stem cells; HUC-MSCs-exo: Human umbilical cord mesenchymal stem cells-derived exosomes; ZEB1: Zinc finger E-box binding homeobox 1; IL-1β: Interleukin 1β; TNF-α: Tumor necrosis factor alpha; IL-6: Interleukin 6; TGF-β1: Transforming growth factor β1; Smad3: Mothers against decapentaplegic homolog 3; α-SMA: Alpha smooth muscle actin; VEGF: Vascular endothelial growth factor; PTEN: Phosphatase and tensin homolog; PI3K: Phosphoinositide 3-kinase; AKT: Protein kinase B.

Citation: Wang HL, Zhang SD, Liu T, Liu LM, Pan XY. Innovations in the treatment of endometrial diseases: Role of human umbilical cord mesenchymal stem cells and their exosomes. World J Stem Cells 2026; 18(5): 115486
URL: https://www.wjgnet.com/1948-0210/full/v18/i5/115486.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i5.115486

Wang HL, Zhang SD, Liu T, Liu LM, Pan XY. Innovations in the treatment of endometrial diseases: Role of human umbilical cord mesenchymal stem cells and their exosomes. World J Stem Cells 2026; 18(5): 115486 [DOI: 10.4252/wjsc.v18.i5.115486]

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