Mesenchymal stem cell-derived microRNAs: Key immunomodulators to prevent ocular tissue degeneration

Figure 1 Summary of mesenchymal stem cells-derived microRNAs, their targets, and signaling pathways involved in ocular diseases. AKT: Protein kinase B; HIF: Hypoxia-inducible factor; HIPK2: Homeodomain-interacting protein kinase 2; HOXC6: Homeobox C6; IL: Interleukin; IRAK1: Interleukin 1-receptor associated kinase 1; MAPK: Mitogen-activated protein kinase; mTOR: Mechanistic target of rapamycin; NF-кB: Nuclear factor kappa B; PI3K: Phosphatidylinositol 3-kinase; PLCG1: Phospholipase C gamma 1; PTEN: Phosphatase and tensin homolog; STAT3: Signal transducer and activator of transcription 3; TGF: Transforming growth factor; TLR4: Toll-like receptor 4.