©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jan 26, 2015; 7(1): 51-64
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.51
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.51
Current progress in use of adipose derived stem cells in peripheral nerve regeneration
Shomari DL Zack-Williams, Peter E Butler, Deepak M Kalaskar, Centre for Nanotechnology and Regenerative Medicine, Division of Surgery and Interventional Science, University College London, WC1E 6BT London, United Kingdom
Peter E Butler, Department of Plastic and Reconstructive Surgery, Royal Free Hampstead NHS Trust Hospital, NW3 2QG London, United Kingdom
Author contributions: All authors have contributed equally to the manuscript.
Correspondence to: Dr. Deepak M Kalaskar, Centre for Nanotechnology and Regenerative Medicine, Division of Surgery and Interventional Science, University College London, 9th Floor, Royal Free Campus, Rowland Hill Street, NW3 2PF London, United Kingdom. d.kalaskar@ucl.ac.uk
Telephone: +44-020-77940500
Received: July 28, 2014
Peer-review started: July 29, 2014
First decision: August 14, 2014
Revised: October 20, 2014
Accepted: October 28, 2014
Article in press: December 16, 2014
Published online: January 26, 2015
Processing time: 169 Days and 19.8 Hours
Peer-review started: July 29, 2014
First decision: August 14, 2014
Revised: October 20, 2014
Accepted: October 28, 2014
Article in press: December 16, 2014
Published online: January 26, 2015
Processing time: 169 Days and 19.8 Hours
Core Tip
Core tip: Adipose derived stem cell differentiation is an area of important active research at present. Since adipose tissue is ubiquitous throughout the body it is an ideal source of cells for regeneration of damaged body parts. In the peripheral nervous system there are currently significant limitations in the methods of treatment and subsequent rehabilitation. Adipose stem cells can express proteins which are similar to schwann cells and are termed schwann like cells. In this review we provide an update on the current methods used in peripheral nerve reconstruction using adipose stem cells.