©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jan 26, 2015; 7(1): 182-185
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.182
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.182
How do resident stem cells repair the damaged myocardium?
Emiko Hayashi, Toru Hosoda, Medical Science Division, Tokai University Institute of Innovative Science and Technology, Kanagawa 259-1193, Japan
Author contributions: Hayashi E drafted the text; Hosoda T finalized the paper.
Supported by The Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (C), No. 25461118
Correspondence to: Toru Hosoda, MD, PhD, Medical Science Division, Tokai University Institute of Innovative Science and Technology, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. hosoda@tokai-u.jp
Telephone: +81-463-931121 Fax: +81-463-953522
Received: July 28, 2014
Peer-review started: July 29, 2014
First decision: September 16, 2014
Revised: September 25, 2014
Accepted: October 23, 2014
Article in press: December 16, 2014
Published online: January 26, 2015
Processing time: 169 Days and 20.6 Hours
Peer-review started: July 29, 2014
First decision: September 16, 2014
Revised: September 25, 2014
Accepted: October 23, 2014
Article in press: December 16, 2014
Published online: January 26, 2015
Processing time: 169 Days and 20.6 Hours
Core Tip
Core tip: The autologous transplantation of cardiac stem cells appeared to be safe and surprisingly effective for a small group of patients with chronic ischemic cardiomyopathy. Their specific feature as resident stem cells, the interaction with the surrounding tissue, and the natural selection during the cell culture process potentially contributed together to the outstanding consequences.