Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Apr 26, 2024; 16(4): 459-461
Published online Apr 26, 2024. doi: 10.4252/wjsc.v16.i4.459
Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation
Yi Li, Qian-Qian Chen, En-Qiang Linghu
Yi Li, Qian-Qian Chen, Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
En-Qiang Linghu, Department of Gastroenterology and Hepatology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Li Y wrote the manuscript; Chen QQ and Linghu EQ revised the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian-Qian Chen, MD, Associate Chief Physician, Associate Professor, Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. qian_qian_chen@163.com
Received: January 8, 2024
Peer-review started: January 8, 2024
First decision: March 9, 2024
Revised: March 12, 2024
Accepted: March 27, 2024
Article in press: March 27, 2024
Published online: April 26, 2024
Processing time: 107 Days and 21.3 Hours
Core Tip

Core Tip: Precondition of mesenchymal stem cells (MSCs) can change the characteristic of MSCs and enhance its biological activity in specific aspects. Both hypoxia and the over-expression of hypoxia-inducible factor 1α can inhibit inflammation. But more mechanisms on precondition MSCs inhibiting inflammation should be revealed to promote curative effect.