Improved prognostic stratification of the revised ninth edition American Joint Committee on Cancer staging system for colorectal cancer

Figure 1 Distribution of pathological staging in the colon cancer and rectal cancer cohorts according to 8^th edition American Joint Committee on Cancer staging system and 9^th edition American Joint Committee on Cancer staging system. CC: Colon cancer; RC: Rectal cancer; AJCC: American Joint Committee on Cancer.

Figure 2 Kaplan-Meier survival curve analysis in the colon cancer cohort. A: Disease-free survival according to the 8^th edition American Joint Committee on Cancer (AJCC) staging system; B: Overall survival according to the 8^th edition AJCC staging system. C: Disease-free survival according to the 9^th edition AJCC staging system. D: Overall survival according to the 9^th edition AJCC staging system. DFS: Disease-free survival; OS: Overall survival; HR: Hazard ratio; TN: Primary Tumor and Regional Lymph Nodes.

Figure 3 Kaplan-Meier survival curve analysis in the rectal cancer cohort. A: Disease-free survival according to the 8^th edition American Joint Committee on Cancer (AJCC) staging system; B: Overall survival according to the 8^th edition AJCC staging system; C: Disease-free survival according to the 9^th edition AJCC staging system; D: Overall survival according to the 9^th edition AJCC staging system. DFS: Disease-free survival; OS: Overall survival; HR: Hazard ratio; TN: Primary Tumor and Regional Lymph Nodes.

Figure 4 Receiver operating characteristic curve analysis. A: Receiver operating characteristic curve (ROC) analysis for disease-free survival (DFS) in the colon cancer (CC) cohort according to 8^th edition American Joint Committee on Cancer (AJCC) staging system; B: ROC analysis for overall survival (OS) in the CC cohort according to 8^th edition AJCC staging system; C: ROC analysis for DFS in the CC cohort according to 9^th edition AJCC staging system; D: ROC analysis for OS in the CC cohort according to 9^th edition AJCC staging system; E: ROC analysis for DFS in the rectal cancer (RC) cohort according to 8^th edition AJCC staging system; F: ROC analysis for OS in the RC cohort according to 8^th edition AJCC staging system; G: ROC analysis for DFS in the RC cohort according to 9^th edition AJCC staging system; H: ROC analysis for OS in the RC cohort according to 9^th edition AJCC staging system. CC: Colon cancer; RC: Rectal cancer; DFS: Disease-free survival; OS: Overall survival; AUC: Area under the curve.