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World J Gastroenterol. May 14, 2026; 32(18): 116229
Published online May 14, 2026. doi: 10.3748/wjg.v32.i18.116229
Published online May 14, 2026. doi: 10.3748/wjg.v32.i18.116229
Clinical manifestations and imaging features of inferior mesenteric vein-related colon ischemia
Xin Jin, Tian-Ming Xu, Ge-Chong Ruan, Xing-Fang Zhang, Xue-Yan Chen, Xiao-Qing Li, Hao Tang, Hui Xu, Qi-Pu Wang, Ji Li, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100730, China
Wei Liu, Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100730, China
Co-corresponding authors: Wei Liu and Ji Li.
Author contributions: Jin X conducted the data collection, statistical analyses, and manuscript drafting; Xu TM, Ruan GC, Zhang XF, Chen XY, Li XQ, Tang H, Xu H, and Wang QP assisted with clinical data acquisition and editing the manuscript; Liu W and Li J supervised the study, made equal contributions as co-corresponding authors. All authors approved the final version to publish.
Supported by National High Level Hospital Clinical Research Funding, No. 2022-PUMCH-D-002; and Beijing Research Ward Excellence Program, No. BRWEP2024W034010110.
Institutional review board statement: This study was approved by the Ethics Committee of Peking Union Medical College Hospital, No. I-23PJ949.
Informed consent statement: Written informed consent or oral consent was given by all patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Ji Li, MD, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China.
Received: November 6, 2025
Revised: January 5, 2026
Accepted: February 26, 2026
Published online: May 14, 2026
Processing time: 182 Days and 0.1 Hours
Revised: January 5, 2026
Accepted: February 26, 2026
Published online: May 14, 2026
Processing time: 182 Days and 0.1 Hours
Core Tip
Core Tip: As a rare subtype of colon ischemia (CI), inferior mesenteric vein (IMV)-related CI often presents with nonspecific symptoms that delay diagnosis. In this study, we reviewed 11 cases from our seven-year experience, highlighting the predominance of middle-aged males, chronic disease, rectal irritation, thrombotic comorbidities, and continuous involvement of the sigmoid and rectum. Identifying both direct and indirect signs of IMV lesions on computed tomography is crucial for accurate diagnosis. Comparative analysis with arterial-related CI patients revealed substantial differences, further highlighting the necessity for prompt recognition and early intervention in IMV-related CI patients.