Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Apr 21, 2026; 32(15): 116083
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.116083
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.116083
Endoscopic transparent cap assisted hemostasis: A multicenter retrospective cohort study
Ömer Küçükdemirci, Department of Gastroenterology, Hakkari State Hospital, Hakkari 30000, Türkiye
Talat Ayyildiz, Ahmet Bektas, Faculty of Medicine, Department of Gastroenterology, Ondokuz Mayis University, Samsun 55139, Türkiye
Berk Bas, Faculty of Medicine, Department of Gastroenterology, Aydın Adnan Menderes University, Aydın 09000, Türkiye
Hasan Eruzun, Department of Gastroenterology, Samsun Training and Research Hospital, Samsun 55200, Türkiye
Nisa Efe, Department of Internal Medicine, Gaziantep City Hospital, Gaziantep 27470, Türkiye
Author contributions: Küçükdemirci Ö made substantial contributions to the conception and design of the study, data acquisition, analysis, and interpretation, drafted the manuscript and made critical revisions for important intellectual content; Ayyildiz T and Bektas A contributed to critical revision of the manuscript and interpretation of data; Bas B, Eruzun H, and Efe N participated in data collection and provided clinical data support; all authors read and approved the final version of the manuscript and agree to be accountable for all aspects of the work.
Institutional review board statement: Approved by the Ondokuz Mayıs University Ethics Committee (approval No. 2024000168-2), permissions obtained from all participating centers.
Informed consent statement: Written informed consent was obtained from all patients.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Data sharing statement: Data are available from the corresponding author upon reasonable request, subject to ethical, legal, and patient confidentiality requirements.
Corresponding author: Ömer Küçükdemirci, MD, Chief Physician, Department of GasHakkâri Merkez/ Hakkari, Hakkari 30000, Türkiye. drkucukdemirci@yahoo.com
Received: November 3, 2025
Revised: December 4, 2025
Accepted: February 3, 2026
Published online: April 21, 2026
Processing time: 164 Days and 12.1 Hours
Revised: December 4, 2025
Accepted: February 3, 2026
Published online: April 21, 2026
Processing time: 164 Days and 12.1 Hours
Core Tip
Core Tip: This multicenter retrospective study compared transparent cap (CAP)-assisted and standard endoscopic hemostasis in non-variceal upper gastrointestinal bleeding (NVUGIB). CAP was used more often in hemodynamically unstable patients and required a greater number of hemostatic techniques but was associated with lower post-admission transfusion rates and volumes. Mortality and hospital stay were comparable between groups. CAP assistance may enhance procedural precision and efficiency without altering systemic outcomes, representing a simple and inexpensive adjunct for improving endoscopic management of NVUGIB.