Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2025; 31(39): 111300
Published online Oct 21, 2025. doi: 10.3748/wjg.v31.i39.111300
Published online Oct 21, 2025. doi: 10.3748/wjg.v31.i39.111300
Budd-Chiari syndrome: Prognostic scores, special populations, and management challenges
Mahassen Elshaer, Department of Gastroenterology, Ahmed Maher Teaching Hospital, Cairo 11617, Al Qāhirah, Egypt
Mahassen Elshaer, Department of Gastroenterology, King Fahad Military Hospital, Jeddah 31932, Makkah al Mukarramah, Saudi Arabia
Mohamed Mahmoud Hafez, Ahmed Gaber Ramadan, Faculty of Medicine, Helwan University, Cairo 11795, Al Qāhirah, Egypt
Khalid Shedeed, Department of Paediatric Haematology and Oncology, Nottingham University Hospital, Nottingham NG7 7NW, United Kingdom
Ahmed Tawheed, Department of Gastroenterology, Al Emadi Hospital, Doha 50000, Qatar
Co-first authors: Mahassen Elshaer and Mohamed Mahmoud Hafez.
Author contributions: Tawheed A designed the overall concept and outline of the manuscript; Ramadan AG and Elshaer M wrote the manuscript; Shedeed K provided critical technical details and revised the manuscript; Hafez MM revised the manuscript; All authors contributed to this article and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ahmed Tawheed, Department of Gastroenterology, Al Emadi Hospital, D-Ring Road, Doha 50000, Qatar. atawheed1990@gmail.com
Received: June 27, 2025
Revised: August 10, 2025
Accepted: September 29, 2025
Published online: October 21, 2025
Processing time: 116 Days and 15.9 Hours
Revised: August 10, 2025
Accepted: September 29, 2025
Published online: October 21, 2025
Processing time: 116 Days and 15.9 Hours
Core Tip
Core Tip: This narrative review provided a comprehensive update on Budd-Chiari syndrome and discussed the advantages and disadvantages of current prognostic scores. It also emphasized special conditions in children, pregnancy, and cases related to myeloproliferative neoplasms. This paper identified key research gaps and advocated for future work on personalized risk assessment, long-term outcome evaluation, and standardized response criteria to improve clinical decision-making in this heterogeneous disease.