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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 7, 2025; 31(37): 110786
Published online Oct 7, 2025. doi: 10.3748/wjg.v31.i37.110786
Diagnostic delays in alcoholic cirrhosis: A cross-sectional study of contributing factors
Zhong-Shang Dai, Zhi Gao, Bo He, Yong-Fang Jiang
Zhong-Shang Dai, Zhi Gao, Bo He, Yong-Fang Jiang, Department of Infectious Diseases, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Co-first authors: Zhong-Shang Dai and Zhi Gao.
Co-corresponding authors: Bo He and Yong-Fang Jiang.
Author contributions: Dai ZS and Gao Z wrote the main manuscript text, prepared figures and tables, and made equal contributions as co-first authors; Dai ZS analyzed all data; He B designed the study; Jiang YF is responsible for data collecting; He B and Jiang YF made equal contributions as co-corresponding authors. All authors have read and approved the final work.
Supported by National Key Research and Development Program of China, No. 2019YFE0190800.
Institutional review board statement: This study was approved by Ethics Committee of Second Xiangya Hospital of Central South University, No. 2020-047.
Informed consent statement: All patients were offered informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Data is available from the corresponding author on a reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Fang Jiang, Department of Infectious Diseases, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. jiangyongfang@csu.edu.cn
Received: June 16, 2025
Revised: July 14, 2025
Accepted: August 27, 2025
Published online: October 7, 2025
Processing time: 102 Days and 12.9 Hours
Core Tip

Core Tip: Among 401 patients with alcoholic cirrhosis in China, the median diagnostic delay was 5 months, with significant variations induced by hospital level (tertiary vs primary) and liver computed tomography evaluation. Factors contributing to diagnostic delay included residence, education, income, drinking patterns and initial diagnostic measures. Lower education, higher daily alcohol intake, lower income and elevated blood ammonia were identified as independent predictors on multivariate analysis. Targeted interventions addressing these modifiable factors are crucial to reducing delays and improving outcomes.