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Letter to the Editor
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2025; 31(33): 110176
Published online Sep 7, 2025. doi: 10.3748/wjg.v31.i33.110176
Relationship between Helicobacter pylori infection and the development of metabolic dysfunction and associated steatotic liver disease
Noube Julie Raissa, Shuo-Yi Yao, Fen Wang
Noube Julie Raissa, Shuo-Yi Yao, Fen Wang, Department of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Co-first authors: Noube Julie Raissa and Shuo-Yi Yao.
Author contributions: Raissa NJ wrote the original draft; Yao SY reviewed and edited the article, and supervised the research; Wang F reviewed and edited the article, acquired the funding, and conceptualized and administrated the project. Raissa NJ and Yao SY contributed equally to this manuscript and are co-first authors. All authors have read and agreed to the published version of the manuscript.
Supported by National Natural Science Foundation of China, No. 82270594.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Fen Wang, MD, Professor, Department of Gastroenterology, The Third Xiangya Hospital of Central South University, No. 138 Tongzi Road, Changsha 410013, Hunan Province, China. wfen-judy@csu.edu.cn
Received: June 3, 2025
Revised: July 6, 2025
Accepted: August 13, 2025
Published online: September 7, 2025
Processing time: 92 Days and 13.5 Hours
Core Tip

Core Tip: This article discussed the relationship between Helicobacter pylori (H. pylori) and the development of metabolic dysfunction and metabolic dysfunction-associated steatotic liver disease (MASLD) based on the study by Ye et al. Their study concluded that H. pylori may play a role in metabolic disturbances (especially in parameters including blood glucose, body mass index, and diastolic blood pressure) and MASLD. There are also other studies in different populations that confirmed the association between H. pylori infection and MASLD.