©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2025; 31(32): 108401
Published online Aug 28, 2025. doi: 10.3748/wjg.v31.i32.108401
Published online Aug 28, 2025. doi: 10.3748/wjg.v31.i32.108401
Ménétrier disease: A clinical review
Ana R Barros, Sara Monteiro, Jorge Silva, Department of Gastroenterology, Unidade Local de Saúde Tâmega e Sousa, Penafiel 4560-136, Porto, Portugal
Author contributions: All authors made substantial contributions to the article; Barros AR performed the literature research and drafted the manuscript; Monteiro S reviewed the manuscript and provided critical input on its intellectual content and structure; Silva J critically revised the manuscript; All authors have approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Ana R Barros, MD, Department of Gastroenterology, Unidade Local de Saúde Tâmega e Sousa, Avenida do Hospital Padre Américo, 210, Penafiel 4560-136, Porto, Portugal. anaritambarros@gmail.com
Received: April 14, 2025
Revised: June 9, 2025
Accepted: August 4, 2025
Published online: August 28, 2025
Processing time: 136 Days and 8.9 Hours
Revised: June 9, 2025
Accepted: August 4, 2025
Published online: August 28, 2025
Processing time: 136 Days and 8.9 Hours
Core Tip
Core Tip: In this clinical review, we explore the pathophysiology, diagnosis, and treatment strategies for Ménétrier disease. From identifying key symptoms such as protein loss and abdominal pain to the role of octreotide and cetuximab in managing the condition, this review offers an in-depth look at current therapeutic approaches. We also highlight the importance of early intervention to prevent complications like gastric cancer, providing essential insights for clinicians in diagnosing and managing this rare disease.