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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2021; 27(24): 3668-3681
Published online Jun 28, 2021. doi: 10.3748/wjg.v27.i24.3668
Disorders of the brain-gut interaction and eating disorders
Stefan-Lucian Popa, Dinu Iuliu Dumitrascu, Dan Lucian Dumitrascu, Giuseppe Chiarioni, Mihaela Fadgyas Stanculete
Mihaela Fadgyas Stanculete, Department of Neurosciences, Discipline of Psychiatry and Pediatric Psychiatry, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca RO 400174, Romania
Giuseppe Chiarioni, Division of Gastroenterology of the University of Verona, AOUI Verona, Verona 37134, Italy
Dan Lucian Dumitrascu, Stefan-Lucian Popa, Department of The Second Medical, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca RO 400174, Cluj, Romania
Dinu Iuliu Dumitrascu, Department of Anatomy, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca RO 400174, Cluj, Romania
Author contributions: Stanculete MF, Chiarioni G, Popa SL, Dumitrascu DI searched the literature, analyzed the results and made substantial contribution to the writing of the manuscript; Dumitrascu DL gave the idea of this review, suggested the methodology, analyzed the results, and revised the manuscript; all authors approved the final version of the manuscript.
Conflict-of-interest statement: No conflict of interest to be declared by all of the Authors.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Giuseppe Chiarioni, MD, Adjunct Professor, Division of Gastroenterology of the University of Verona, AOUI Verona, Piazzale LA Scuro 10, Verona 37134, Italy. chiarioni@alice.it
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: February 28, 2021
Revised: March 12, 2021
Accepted: June 3, 2021
Article in press: June 3, 2021
Published online: June 28, 2021
Processing time: 153 Days and 14.8 Hours
Core Tip

Core Tip: Functional gastrointestinal disorders actually defined disorders of the brain-gut interaction (DGBI) by the new Rome IV criteria share similar symptoms with eating disorders (ED). Etiology is ill defined for both disorders thou a negative impact on quality of life and a high socio-economic burden is reported. We looked for the comorbidity of DGBI and ED, in order to find out where there is an association and a cause-effect relationship.

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