In 2016, the World Journal of Hepatology (WJH) has published the 26^th issue which containing 5 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Cholangiocarcinoma, gone without the Wnt?”, an Editorial by Frank G Schaap, PhD, et al from Department of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, The Netherlands; (2) “Immune response to hepatitis B virus vaccine in celiac subjects at diagnosis”, an Original Article by Dr. Salvatore Leonardi, Professor, et al from Department of Medical and Pediatric Sciences, University of Catania, Italy, etc. We invite you to peruse all 5 articles in this issue, as they present the latest research progress/findings and provide insightful comments in hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 8, Issue 26, September 18, 2016.

Figure 1 The cover of the issue. Editorial Board Member of World Journal of Hepatology, Rui-An Xu, PhD, Director, Professor, Engineering Research Center of Molecular Medicine, Ministry of Education, Xiamen 361021, Fujian Province, China

The WJH is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of hepatology. It was launched on October 31, 2009 and is published three issues per month (36 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage hepatologists worldwide to submit manuscripts to the WJH describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at: http://www.wjgnet.com/1948-5182/e-journal.htm.