In 2016, the World Journal of Gastroenterology (WJG) has published the 31^st issue which containing 18 articles including one Editorial, 11 Reviews and five Original Articles and one Case Reports, contributed by scientists worldwide. Among these comprehensive articles are (1) “Endoscopic and non-endoscopic approaches for the management of radiation-induced rectal bleeding”, a Review article by David Schreiber, MD, et al from Department of Radiation Oncology, VA NY Harbor Healthcare System, United States; (2) “Metabolic aspects of adult patients with nonalcoholic fatty liver disease”, a Review article by Ludovico Abenavoli, MD, PhD, et al from Department of Health Sciences, University Magna Graecia, Italy; and (3) “Nanovectors for anti-cancer drug delivery in the treatment of advanced pancreatic adenocarcinoma”, a Minireview article by Chung-Tsen Hsueh, MD, PhD, et al from Division of Medical Oncology and Hematology, Department of Internal Medicine, Loma Linda University, United States, etc. We invite you to peruse all 18 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 22, Issue 31, August 21, 2016.

Figure 1 The cover of the issue. Editorial board member of World Journal of Gastroenterology, Satoru Kakizaki, MD, PhD, Associate Professor, Lecturer, Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 3718511, Japan.

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at: http://www.wjgnet.com/1007-9327/e-journal.htm.