In 2018, the World Journal of Gastroenterology (WJG) has published the 25^th issue which containing 11 articles including 5 reviews, 5 original articles, and 1 case report contributed by scientists worldwide. Among these comprehensive articles are (1) “Role of microRNAs in the main molecular pathways of hepatocellular carcinoma”, a review by Michela Visani, PhD, et al from Molecular Pathology Unit, Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale), School of Medicine, Bologna University, Italy; (2) “Intra-individual comparison of therapeutic responses to vascular disrupting agent CA4P between rodent primary and secondary liver cancers”, a basic study by Yi-Cheng Ni, MD, PhD, Full Professor, et al from Theragnostic Laboratory, Department of Imaging and Pathology, Biomedical Group, KU Leuven, Belgium; and (3) “Gastric cancer in Alaska Native people: A cancer health disparity”, a retrospective study by Holly A Martinson, PhD, Assistant Professor, et al from WWAMI School of Medical Education, University of Alaska Anchorage, United States, etc. We invite you to peruse all 11 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 24, Issue 25, July 7, 2018.

Figure 1 The cover of the issue. Editorial board member of World Journal of Gastroenterology, Dar-In Tai, MD, PhD, Attending Doctor, Chief Doctor, Professor, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taipei 105, Taiwan

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue.