In 2017, the World Journal of Nephrology (WJN) has published the 1^st issue which containing 8 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Hypertonicity: Clinical entities, manifestations and treatment”, a Review by Antonios H Tzamaloukas, MD, MACP, et al from the Section of Nephrology, Medicine Service (111C), Raymond G. Murphy Veterans Affairs Medical Center, United States; (2) “Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism”, an Original Article by Dr. Simon JM Welham, et al from the Division of Nutritional Sciences, School of Biosciences, University of Nottingham, United Kingdom; and (3) “Severe hyperkalemia following blood transfusions: Is there a link?”, a Case Report by Moses S Elisaf, MD, FASA, FRPSH, Professor, et al from the Department of Internal Medicine, Medical School, University of Ioannina, Greece, etc. We invite you to peruse all 8 articles in this issue, as they present the latest research progress/findings and provide insightful comments in nephrology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 6, Issue 1, January 6, 2017.

Figure 1 The cover of the issue. Editorial Board Member of World Journal of Nephrology, Saeed Taheri, MD, Doctor, Department of Medicine, Dr. Taheri Medical Research Group, Tehran 15146-13914, Iran

The WJN is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of nephrology. It was launched on February 6, 2012 and is published bimonthly (6 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage nephrologists worldwide to submit manuscripts to the WJN describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at: http://www.wjgnet.com/2220-6124/e-journal.htm.