In 2016, the World Journal of Cardiology (WJC) has published the 12^nd issue which containing 6 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Hematological disorders and pulmonary hypertension”, a Review by Rajamma Mathew, MD, et al from the Section of Pediatric Cardiology, New York Medical College, United States; and (2) “Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves: A single-center experience”, an Original Article by Bernard Chevalier, MD, et al from the Department of Cardiology, Générale de Santé, Institut Cardiovasculaire Paris-Sud - Hôpital Privé Jacques Cartier, France, etc. We invite you to peruse all 6 articles in this issue, as they present the latest research progress/findings and provide insightful comments in cardiology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 8, Issue 12, December 26, 2016.

Figure 1 The cover of the issue. Editorial Board Member of World Journal of Cardiology, Joaquin De Haro, MD, PhD, Doctor, Professor, Staff Physician, Surgeon, Angiology and Vascular Surgery Department, Hospital Universitario Getafe, 28905 Madrid, Spain

The WJC is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of cardiology. It was launched on December 31, 2009 and is published monthly (12 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage cardiologists worldwide to submit manuscripts to the WJC describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at http://www.wjgnet.com/1949-8462/e-journal.htm.