In 2016, the World Journal of Transplantation (WJT) has published the 4^th issue which containing 22 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Complement related kidney diseases: Recurrence after transplantation”, a Review by Maurizio Salvadori, MD, et al from the Department of Renal Transplantation, Careggi University Hospital, Italy; (2) “Tacrolimus confers lower acute rejection rates and better renal allograft survival compared to cyclosporine”, an Original Article by Maria Aurora Posadas Salas, MD, et al from the Department of Medicine, Medical University of South Carolina, United States; and (3) “Outcomes in randomized controlled trials of exercise interventions in solid organ transplant”, a Systematic Reviews by Tania Janaudis-Ferreira, PhD, et al from the School of Physical and Occupational Therapy, McGill University, Canada, etc. We invite you to peruse all 22 articles in this issue, as they present the latest research progress/findings and provide insightful comments in transplantation that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 6, Issue 4, December 24, 2016.

Figure 1 The cover of the issue. Editorial Board Member of World Journal of Transplantation, Archil Chkhotua, MD, Director, Professor, Department of Urology, National Center of Urology, Tbilisi 0144, Georgia

The WJT is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of transplantation. It was launched on December 24, 2011 and is published trimonthly (4 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage transplantation specialists worldwide to submit manuscripts to the WJT describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at:http://www.wjgnet.com/2220-3230/e-journal.htm.