In 2016, the World Journal of Gastrointestinal Pharmacology and Therapeutics (WJGPT) has published the 4^th issue which containing 14 articles contributed by scientists worldwide. Among these comprehensive articles are (1) “Bilirubin in coronary artery disease: Cytotoxic or protective?”, a Review by Nancy Gupta, MD, et al from the Department of Medicine, Westchester Medical Center, New York Medical College, United States; (2) “Widespread use of gastric acid inhibitors in infants: Are they needed? Are they safe?”, a Minireviews by Dr. Usha Krishnan, et al from the Department of Paediatric Gastroenterology, Sydney Children’s Hospital, Australia; and (3) “Family history and disease outcomes in patients with Crohn’s disease: A comparison between China and the United States”, an Original Article by Susan Hutfless, PhD, Assistant Professor, Director, et al from the Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University, United States, etc. We invite you to peruse all 14 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastrointestinal pharmacology and therapeutics that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 7, Issue 4, November 6, 2016.

Figure 1 The cover of the issue.Editorial Board Member of World Journal of Gastrointestinal Pharmacology and Therapeutics, Nanne KH De Boer, MD, PhD, Professor, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam 1007 MB, The Netherlands

The WJGPT is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of gastrointestinal pharmacology and therapeutics. It was launched on February 6, 2010 and is published trimonthly (4 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.

We encourage pharmacology and therapeutics specialists worldwide to submit manuscripts to the WJGPT describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at:http://www.wjgnet.com/2150-5349/e-journal.htm.