In 2016, the World Journal of Gastroenterology (WJG) has published the 38^th issue which containing 21 articles including five Reviews, 13 Original Articles, two Case Reports and one Letters To The Editor contributed by scientists worldwide. Among these comprehensive articles are (1) “Antiviral therapy of hepatitis C as curative treatment of indolent B-cell lymphoma”, a Review article by Dr. Carlo Visco, et al from Department of Cell Therapy and Hematology, San Bortolo Hospital, Italy; (2) “Elucidation of the early infection machinery of hepatitis B virus by using bio-nanocapsule”, a Review article by Shun’ichi Kuroda, PhD, Professor, et al from Department of Biomolecular Science and Reaction, The Institute of Scientific and Industrial Research, Osaka University, Japan; and (3) “Racial/ethnic disparities in hepatocellular carcinoma treatment and survival in California, 1988-2012”, an Observational Study article by Moon S Chen Jr, PhD, MPH., Professor, et al from Cancer Control/Cancer Health Disparities, University of California, Davis Comprehensive Cancer Center, United States, etc. We invite you to peruse all 21 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

This journal is an open-access journal which allows free immediate access to all full-text articles. For details, please visit: Volume 22, Issue 38, October 14, 2016.

Figure 1 The cover of the issue. Editorial board member of World Journal of Gastroenterology, Hassan Ashktorab, DA, Adjunct Professor, Director, Professor, Medicine and Cancer Center, Howard University, Washington DC, DC 20059, United States.

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue, at: http://www.wjgnet.com/1007-9327/e-journal.htm.