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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Dec 18, 2025; 13(4): 108504
Published online Dec 18, 2025. doi: 10.13105/wjma.v13.i4.108504
Published online Dec 18, 2025. doi: 10.13105/wjma.v13.i4.108504
Association of the rs1333048 polymorphism in the ANRIL gene with different clinical forms of periodontitis: A meta-analysis
Felipe Rodolfo Pereira da Silva, André Victor Oliveira Monteiro, Medicine College, Federal University Para, Altamira 68373-106, Pará, Brazil
Alessandro Luiz Araújo Bentes Leal, José Rogério Souza Monteiro, Ana Carolina Alves de Oliveira, Adenilson Leão Pereira, Medicine College, Federal University of Para, Altamira 68372-040, Pará, Brazil
Juliana Gomes Galeno, Anna Carolina Toledo da Cunha Pereira, Daniel Fernando Pereira Vasconcelos, Department of Biomedicine, Parnaiba Delta Federal University, Parnaiba 64202-020, Piauí, Brazil
Francisco Angelis Herrera Araujo, Kamilly de Oliveira Tavares, Department of Pharmacy, Serra Dourada College, Altamira 68378-001, Pará, Brazil
Author contributions: Da Silva FRP and Vasconcelos DFP contributed to the study design; da Silva FRP and Leal ALAB contributed to data collection; da Silva FRP and Galeno JG contributed to statistical analyses; da Silva FRP, Araujo FAH, Tavares KO, and Monteiro AVO contributed to data interpretation; da Silva FRP, Monteiro JRS, de Oliveira ACA, Pereira AL, Monteiro AVO, and Pereira ACTC contributed to manuscript preparation of the manuscript; da Silva FRP contributed to the literature search.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adenilson Leão Pereira, Professor, Medicine College, Federal Univer
Received: April 16, 2025
Revised: May 16, 2025
Accepted: September 18, 2025
Published online: December 18, 2025
Processing time: 246 Days and 16.9 Hours
Revised: May 16, 2025
Accepted: September 18, 2025
Published online: December 18, 2025
Processing time: 246 Days and 16.9 Hours
Core Tip
Core Tip: Many case-control studies have identified a relationship between the rs1333048 polymorphism and periodontitis. However, the impact of this genetic variation on the clinical aspect of periodontitis is still unknown.