Clinical outcomes and 5-year follow-up results of keratosis pilaris treated by a high concentration of glycolic acid

Table 1 Global esthetic improvement scale

Grading	Description
Excellent improvement	The best aesthetic results are achieved after treatment
Significant improvement	There is significant improvement in appearance compared to the initial situation
Some improvement	Compared with the initial situation, there is obvious improvement
No improvement	The appearance is essentially the same as the initial situation
Worse	The appearance is worse than the initial situation

Table 2 Changes in the number of keratotic papules before and after treatment of the 25 study cases

Case	Day 0	Day 20	Day 40	Day 60	Day 80
1	52	25	20	16	10
2	26	22	21	15	14
3	95	80	71	58	28
4	46	38	32	25	24
5	58	49	33	29	21
6	35	23	19	14	10
7	80	58	43	37	26
8	66	47	58	23	19
9	35	21	18	15	11
10	75	59	50	38	36
11	38	25	16	15	12
12	43	37	33	26	13
13	55	53	48	43	42
14	61	30	22	15	11
15	48	45	41	31	25
16	57	55	51	45	43
17	39	33	28	21	14
18	72	65	55	43	37
19	28	22	19	12	7
20	30	27	21	16	12
21	42	38	33	27	23
22	58	53	45	37	29
23	65	62	57	49	33
24	36	29	23	16	9
25	88	80	66	52	45
Average	53.12 ± 18.49	43.04 ± 17.53	36.92 ± 16.24	28.72 ± 13.51	22.16 ± 11.61

Data are the number of keratotic papules before treatment and on days 20, 40, 60, and 80.

Table 3 Changes in melanin content, skin hemoglobin content, and skin lightness before and after treatment

Measurement index	Pretreatment	Day 20	Day 40	Day 60	Day 80	5 yr
M value	219.48 ± 64.09	215.80 ± 63.87	213.12 ± 60.421	203.92 ± 58.621	197.04 ± 59.231	223.56 ± 45.51
E value	261.76 ± 60.31	256.16 ± 64.00	258.48 ± 67.86	248.36 ± 62.501	242.2 ± 66.391	255.13 ± 51.25
L value	61.41 ± 4.23	61.94 ± 4.17	62.20 ± 3.941	62.57 ± 3.781	63.24 ± 3.601	61.89 ± 3.83

¹P < 0.05 vs pretreatment. E: Skin hemoglobin content; L: Skin lightness; M: Melanin content.

Table 4 Self-evaluation status of subjects

	Day 20	Day 40	Day 60	Day 80	5 yr
Excellent improvement	0	0	1	1	0
Significant improvement	2	4	5	7	0
Some improvement	9	11	12	11	3
No change	12	10	7	6	4
Worse	0	0	0	0	2
Total	25	25	25	25	9

Data are the number of subjects.