Copyright
©The Author(s) 2020.
World J Clin Cases. Oct 26, 2020; 8(20): 4946-4952
Published online Oct 26, 2020. doi: 10.12998/wjcc.v8.i20.4946
Published online Oct 26, 2020. doi: 10.12998/wjcc.v8.i20.4946
Diagnostic criteria for HLH fulfilled, at least 5 of the 8 criteria below | First admission | Post-treatment | Second admission | Third admission |
Fever | Y | N | Y | Y |
Splenomegaly | Y | N | N | N |
Cytopenia, affecting 2 of 3 lineages in the peripheral blood | Y | N | N | N |
Hemoglobin < 9 g/dL | Y | N | N | N |
Platelets < 100 × 109/L | Y | N | N | N |
Neutrophils < 1.0 × 109/L | Y | N | N | N |
Hypertriglyceridemia (fasting ≥ 3.0 mmol/L) and/or hypofibrinogenemia (≤ 150 mg/dL) | Y | N | N | N |
Hemophagocytosis in bone marrow or spleen or lymph nodes (no evidence of malignancy) | Y | NA | NA | NA |
Low or absent natural killer cell activity | NA | NA | NA | NA |
Ferritin ≥ 500 ng/mL | Y | N | N | N |
Soluble cluster of differentiation 25 (i.e. soluble interleukin 2 receptor) ≥ 2400 U/mL | NA | NA | NA | NA |
- Citation: Miao SX, Wu ZQ, Xu HG. Systemic autoimmune abnormalities complicated by cytomegalovirus-induced hemophagocytic lymphohistiocytosis: A case report. World J Clin Cases 2020; 8(20): 4946-4952
- URL: https://www.wjgnet.com/2307-8960/full/v8/i20/4946.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v8.i20.4946