Combination of endoscopic submucosal dissection and laparoscopic sentinel lymph node dissection in early mucinous gastric cancer: Role of lymph node metastasis

Table 1 Univariate analysis of potential risk factors for positive lymph node metastasis

Factor	Lymph node metastasis
	Positive number	P value
Age (yr)		0.839
< 60 (n = 19)	4
≥ 60 (n = 12)	3	0.850
Sex
Male (n = 21)
Female (n = 10)
Macroscopic type
I (n = 2)	0
II (n = 22)	6
III (n = 7)	1
Family medical history		0.904
Positive (n = 5)	1
Negative (n = 26)	6
Location		0.317
Upper (n = 3)	1
Middle (n = 8)	0
Lower (n = 20)	6
Number of tumors		0.490
Single (n = 29)	7
Multitude (n = 2)	0
Depth of invasion		0.036
Mucosa (n = 22)	2
Submucosa (n = 9)	5
Tumor size in diameter		0.040
≤ 2 cm (n = 25)	3
> 2 cm (n = 6)	4
Lymphatic vessel involvement		0.003
Negative (n = 23)	1
Positive (n = 8)	6
Ulceration		0.589
Negative (n = 25)	5
Positive (n = 6)	2

Table 2 Multivariate analysis of potential risk factors for positive lymph node metastasis

Factor	Hazard ratio	95%CI	P value
Depth of invasion	7.342	1.127-33.256	0.039
Mucosa
Submucosa
Tumor size	9.158	1.348-29.133	0.044
≤ 2 cm
> 2 cm
Lymphatic vessel involvement	27.749	1.821-33.14	0.019
Negative			0
Positive

CI: Confidence interval.