Li H, Zhao LL, Zhang XC, Liu DX, Wang GY, Huo ZB, Chen SB. Combination of endoscopic submucosal dissection and laparoscopic sentinel lymph node dissection in early mucinous gastric cancer: Role of lymph node metastasis. World J Clin Cases 2020; 8(16): 3474-3482 [PMID: 32913854 DOI: 10.12998/wjcc.v8.i16.3474]
Corresponding Author of This Article
Zhi-Bin Huo, PhD, Professor, Institute of Cancer Control, Xingtai People’s Hospital, No. 16 Hongxing Street, Xingtai 054001, Hebei Province, China. zhibinhwcwk@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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Li H, Zhao LL, Zhang XC, Liu DX, Wang GY, Huo ZB, Chen SB. Combination of endoscopic submucosal dissection and laparoscopic sentinel lymph node dissection in early mucinous gastric cancer: Role of lymph node metastasis. World J Clin Cases 2020; 8(16): 3474-3482 [PMID: 32913854 DOI: 10.12998/wjcc.v8.i16.3474]
World J Clin Cases. Aug 26, 2020; 8(16): 3474-3482 Published online Aug 26, 2020. doi: 10.12998/wjcc.v8.i16.3474
Combination of endoscopic submucosal dissection and laparoscopic sentinel lymph node dissection in early mucinous gastric cancer: Role of lymph node metastasis
Hua Li, Li-Li Zhao, Xiao-Chong Zhang, Deng-Xiang Liu, Zhi-Bin Huo, Shu-Bo Chen, Institute of Cancer Control, Xingtai People’s Hospital, Xingtai 054001, Hebei Province, China
Gui-Ying Wang, Department of General Surgery, Fourth Affiliated Hospital of Hebei Medial University, Shijiazhuang 050000, Hebei Province, China
Author contributions: Li H, Zhao LL, Zhang XC, and Liu DX contributed equally to this work; Huo ZB, Chen SB, and Wang GY should be regarded as co-corresponding authors of this article; Huo ZB, Chen SB, and Wang GY designed the research; Li H analyzed the data and drafted the manuscript; Zhao LL and Zhang XC revised the manuscript critically for important intellectual content and contributed to the data analysis; Liu DX helped draft the manuscript; all authors read and approved the final manuscript.
Institutional review board statement: This study is a retrospective study for the data of patients collected from the Department of Surgical Oncology, Xing Tai People’s Hospital during 1988-2016. No human body was involved in this study. According to our hospital’s policy, this study does not require an approval by the hospital institutional review board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No conflict of interest is declared by the authors.
Data sharing statement: No additional data are available.
Corresponding author: Zhi-Bin Huo, PhD, Professor, Institute of Cancer Control, Xingtai People’s Hospital, No. 16 Hongxing Street, Xingtai 054001, Hebei Province, China. zhibinhwcwk@126.com
Received: March 20, 2020 Peer-review started: March 20, 2020 First decision: April 29, 2020 Revised: July 5, 2020 Accepted: July 16, 2020 Article in press: July 16, 2020 Published online: August 26, 2020 Processing time: 158 Days and 0.5 Hours
Core Tip
Core tip: A combination of laparoscopic sentinel lymph node dissection (SLND) and endoscopic submucosal dissection (ESD) may avoid unnecessary surgical intervention in early mucinous gastric cancer (EMGC) patients having a potential risk of positive lymph node metastasis (pLNM). ESD allows the complete local resection of the primary tumor, and SLND enables the confirmation of lymph node status. We performed this current retrospective study to identify risk factors that are predictive factor for pLNM in EMGC and to establish a primary criterion and working flowchart to expand the possibility of using ESD and SLND for the treatment of EMGC. The combination of ESD and SLND could be recommended as an effective, minimally invasive treatment for EMGC patients with a high risk of pLNM.
