Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery

Table 1 Demographic and preoperative data of the study series

	Combination (SD) n = 30	General (SD) n = 31	P-value
AGE	61.7 ± 9.9	63.6 ± 9.7	0.520
BMI	24.2 ± 3.01	26.1 ± 3.3	0.111
Mean blood Pressure	91.3 ± 12.8	95.2 ± 15	0.276
Creatinine	0.86 ± 0.31	0.80 ± 0.27	0.427
Glucose	108.9 ± 24.3	103.9 ± 18.9	0.344
Hemoglobin	12.9 ± 1.51	13.2 ± 1.85	0.568
Hematocrit	38.8 ± 4.42	39.1 ± 5.33	0.817
Platelets	222 ± 77.2	220 ± 83.6	0.862
INR	0.97 ± 0.09	0.98 ± 0.10	0.885
PA	106.7 ± 17.6	105.1 ± 174.6	0.817
aPTT	29.1 ± 2.32	29.3 ± 2.73	0.976

BMI: Body mass index; PA: Prothrombin activity; aPTT: Activated partial thromboplastin time; INR: International normalized ratio; SD: Standart desviation.

Table 2 International normalized ratio according to the type of anesthesia and type of resection

Time	Anesthesia	Resection	Mean	St. error	SD
0	Combi	Major	1.217	0.032	0.130
24	Combi	Major	1.516	0.053	0.219
48	Combi	Major	1.556	0.074	0.303
72	Combi	Major	1.265	0.042	0.173
120	Combi	Major	1.062	0.028	0.115
0	General	Major	1.207	0.035	0.134
24	General	Major	1.425	0.074	0.287
48	General	Major	1.542	0.099	0.385
72	General	Major	1.287	0.063	0.246
120	General	Major	1.124	0.052	0.203
0	Combi	Minor	1.048	0.049	0.154
24	Combi	Minor	1.171	0.057	0.182
48	Combi	Minor	1.160	0.098	0.309
72	Combi	Minor	1.065	0.074	0.233
120	Combi	Minor	0.979	0.048	0.153
0	General	Minor	1.142	0.121	0.271
24	General	Minor	1.220	0.027	0.060
48	General	Minor	1.174	0.078	0.175
72	General	Minor	1.040	0.071	0.160
120	General	Minor	1.018	0.088	0.197

Combi: Combined anesthesia; General: General anesthesia; SD: Standart desviation.

Table 3 Evolution of prothrombin activity over time according to the type of anesthesia and type of resection

Time	Anesthesia	Resection	Mean	St. error	SD
0	Combi	Major	76.529	2.154	8.882
24	Combi	Major	58.824	2.661	10.973
48	Combi	Major	59.529	3.245	13.380
72	Combi	Major	76.353	3.240	13.360
120	Combi	Major	95.118	2.724	11.230
0	General	Major	78.133	3.275	12.682
24	General	Major	65.333	5.123	19.841
48	General	Major	60.200	5.206	20.164
72	General	Major	74.467	5.130	19.867
120	General	Major	87.533	4.916	19.041
0	Combi	Minor	95.800	5.781	18.281
24	Combi	Minor	81.600	5.053	15.981
48	Combi	Minor	82.500	5.905	18.674
72	Combi	Minor	94.000	7.335	23.195
120	Combi	Minor	101.600	4.960	15.686
0	General	Minor	88.800	8.540	19.097
24	General	Minor	75.000	2.408	5.385
48	General	Minor	79.000	6.716	15.017
72	General	Minor	92.800	9.019	20.167
120	General	Minor	99.000	9.555	21.366

Combi: Combined anesthesia; General: General anesthesia; SD: Standart desviation.