Association of lower urinary tract symptoms with restless leg syndrome and impaired somnolence pattern in middle aged and elderly men

Table 1 Domain-wise comparison of International Prostate Symptom Score in lower urinary tract symptoms patients, mean ± SD/median (interquartile range)

IPSS score domains	RLS (n = 113)	Non-RLS (n = 150)	P value
Incomplete emptying	3.19 ± 2.025, 4.00 (1.00-5.00)	2.33 ± 1.785, 2.00 (1.00-4.00)	< 0.001a
Frequency	2.76 ± 2.084, 3.00 (0.00-5.00)	2.33 ± 1.786, 2.00 (1.00-4.00)	0.08
Intermittency	2.85 ± 2.151, 3.00 (0.00-5.00)	1.99 ± 1.753, 2.00 (0.00-3.00)	< 0.001 a
Urgency	2.61 ± 2.185, 3.00 (0.00-5.00)	2.31 ± 1.761, 2.00 (1.00-3.25)	0.322
Weak stream	2.84 ± 2.145, 3.00 (0.00-5.00)	1.87 ± 1.803, 1.50 (0.00-3.00)	< 0.001a
Straining	2.30 ± 2.057, 2.00 (0.00-5.00)	1.48 ± 1.625, 1.00 (0.00-2.00)	< 0.05a
Nocturia	3.16 ± 1.579, 3.00 (2.00-5.00)	2.47 ± 1.612, 2.00 (1.00-4.00)	< 0.001a
Total	19.78 ± 6.731, 20.00 (15.00-24.00)	16.55 ± 7.376, 16.00 (11.00-20.00)	< 0.001a

^aP < 0.05.

RLS: Restless legs syndrome; IPSS: International Prostate Symptom Score.

Table 2 Domain-wise comparison of Pittsburgh Sleep Quality Index score in lower urinary tract symptoms patients (n = 263), mean ± SD/median (interquartile range)

PSQI score domains	RLS (n = 113)	Non-RLS (n = 150)	P value
Subjective sleep quality	1.01 ± 1.184, 0.00 (0.00-2.00)	0.70 ± 0.749, 1.00 (0.00-1.00)	0.177
Sleep latency	0.89 ± 1.089, 0.00 (0.00-2.00)	0.84 ± 0.844, 1.00 (0.00-1.00)	0.709
Sleep duration	088 ± 1.103, 0.00 (0.00-2.00)	0.56 ± 0.719, 0.00 (0.00-1.00)	0.107
Habitual sleep	0.93 ± 1.208, 0.00 (0.00-2.00)	0.78 ± 0.866, 1.00 (0.00-1.00)	0.917
Sleep disturbances	0.84 ± 1.040, 0.00 (0.00-2.00)	0.69 ± 0.759, 1.00 (0.00-1.00)	0.734
Use of sleeping medication	0.77 ± 1.207, 0.00 (0.00-1.00)	0.38 ± 0.527, 0.00 (0.00-1.00)	< 0.05a
Day time dysfunction	0.94 ± 1.144, 0.00 (0.00-2.00)	0.52 ± 0.610, 0.00 (0.00-1.00)	< 0.05a
Total	6.48 ± 7.169, 0.00 (0.00-13.00)	6.31 ± 5.225, 7.00 (0.00-11.00)	0.824

^aP < 0.05.

RLS: Restless legs syndrome; PSQI: Pittsburgh Sleep Quality Index.

Table 3 Symptoms-wise comparison of correlation between International Prostate Symptom Score and Pittsburgh Sleep Quality Index

LUTS symptoms and IPSS score	RLS		Non-RLS
	Correlation coefficient1	P value	Correlation coefficient1	P value
Incomplete emptying	0.025	0.79	-0.123	0.13
Frequency	0.195	< 0.05a	-0.047	0.56
Intermittency	-0.043	0.65	-0.040	0.63
Urgency	0.108	0.25	0.015	0.85
Weak stream	0.057	0.54	-0.106	0.19
Straining	-0.047	0.62	0.112	0.17
Nocturia	-0.001	0.99	-0.277	< 0.05a
IPSS	0.290	< 0.05a	-0.144	0.07

¹Spearman correlation coefficient.

^aP < 0.05.

IPSS: International Prostate Symptom Score; LUTS: Lower urinary tract symptoms; RLS: Restless legs syndrome.