BPG is committed to discovery and dissemination of knowledge
Case Report
Copyright: ©Author(s) 2026.
World J Clin Cases. Apr 6, 2026; 14(10): 119456
Published online Apr 6, 2026. doi: 10.12998/wjcc.v14.i10.119456
Table 1 Literature review of case reports on anorectal mucosal melanoma in the past 5 years
No.
Ref.
Gender (M/F)
Age (year)
Clinical symptoms
Tumor size (cm)
Tumor location
Endoscopic features
Hyperpigmentation (Y/N)
1Hokama et al[21], 2021M65Hematochezia, anal pain/RectumUlcerating typeN
2Angelo et al[20], 2024F61Rectal bleeding, prolapsed anal mass4.00 Anal canalNodular typeN
3De la Mora-Romero et al[22], 2024F50Hematochezia, perianal pain4.00 Anal canalPolypoid typeY
4Zhong et al[23], 2025F51Hematochezia2.50 Colorectal junctionPolypoid type/
5Parajuli et al[24], 2025M71Perianal pain, pain during defecation6.00 RectumNodular typeY
6Ren et al[25], 2025F67Hematochezia, altered bowel habits1.50 Near the dentate lineNodular type33.3% with hyperpigmentation
F70Hematochezia2.00 Near the dentate lineCauliflower-like
F67Hematochezia3.00 Near the dentate lineCauliflower-like
F53Altered bowel habits3.00 Near the dentate lineCauliflower-like
F52Prolapsed anal mass2.00 Near the dentate lineCauliflower-like
F69Hematochezia2.00 Near the dentate lineNodular type
F56Sensation of anal heaviness3.00 Near the dentate lineCauliflower-like
M50Asymptomatic0.50 Near the dentate lineNodular type
F39Sensation of anal heaviness3.00 Near the dentate lineCauliflower-like
7Dubey et al[26], 2025F56Rectal bleeding12.40 RectumUlcerating type/
8El Achchi et al[27], 2025F61Rectal syndrome, anemia /PerianalUlcerating typeY
F65Hematochezia, rectal syndrome6.00 RectumNodular typeY
9Khan et al[28], 2024F71Rectal bleeding, constipation4.00 PerianalNodular type/
10Souhaib et al[29], 2024M73Rectal syndrome, rectal bleeding5.00 PerianalUlcerating typeY
11Wong et al[30], 2024F61Anal pain, rectal bleeding, altered bowel habits1.00 PerianalPolypoid typeY
12Thatipalli et al[31], 2024M67Altered bowel habits, pain during defecation, rectal bleeding 7.00 RectumUlcerating typeY
13Xiong et al[32], 2024F58Hematochezia2.20 8 cm from the anal marginNodular typeY
14Amoako-Teming et al[33], 2023M71Anemia, rectal bleeding1.00 Anal canalUlcerating type/
15Elouali et al[34], 2023M63Tenesmus and pain preceding evacuations, rectal bleeding3.00 3 cm from the anal marginUlcerating typeY
16El Youssi et al[35], 2023F60Altered bowel habits, pain preceding evacuations5.00 4 cm from the anal marginUlcerating typeY
17Alazki et al[36], 2023F57Lower abdominal pain2.50 3 cm from the anal marginPolypoid typeY
18Biswas et al[37], 2023F69Pain preceding evacuations, rectal bleeding/Anorectal junctionNodular type/
19Apostu et al[38], 2021F66Tenesmus and pain preceding evacuations, rectal bleeding2.80 Anorectal junctionCauliflower-likeN
20Nafees et al[4], 2020M69Tenesmus and pain preceding evacuations16.00 RectumUlcerating typeN
21Li et al[39], 2020F85Fecal incontinence1.00 Near the dentate linePolypoid typeY
22Dai et al[40], 2020F48Hematochezia, anal pain3.00 3 cm from the anal marginNodular typeN
23Lian et al[41], 2020F43Asymptomatic1.00 Anal canalPolypoid typeY