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©The Author(s) 2024.
World J Clin Cases. Dec 6, 2024; 12(34): 6696-6704
Published online Dec 6, 2024. doi: 10.12998/wjcc.v12.i34.6696
Published online Dec 6, 2024. doi: 10.12998/wjcc.v12.i34.6696
Table 1 Demographic data and clinical manifestations of the enrolled patients (n = 51)
| n (%) | Benign | Malignant | P value | ||
| Sex | Male | 29 (56.8) | 10 (71.4) | 19 (51.4) | 0.329 |
| Female | 22 (43.2) | 4 (28.6) | 18 (48.6) | ||
| Age | 58.9 ± 18.8 | 45.9 ± 18.7 | 63.9 ± 16.5 | 0.002 | |
| Indication | Suspected small intestinal tumor | 27 (52.9) | 7 (50.0) | 20 (55.3) | 0.558 |
| Obscure GI bleeding | 20 (39.2) | 5 (35.7) | 15 (39.5) | ||
| Bowel obstruction | 1 (2.0) | 0 (0.0) | 1 (2.6) | ||
| Abdominal pain | 3 (5.9) | 2 (14.3) | 1 (2.6) | ||
| Endoscopy route | Antegrade | 24 (47.1) | 3 (21.4) | 21 (56.8) | 0.074 |
| Retrograde | 20 (39.2) | 8 (57.1) | 12 (32.4) | ||
| Bidirectional | 7 (13.7) | 3 (21.4) | 4 (10.8) | ||
| Imaging study | Not performed | 4 (7.8) | 4 (28.6) | 0 (0.0) | 0.004 |
| CT/MRI | 47 (92.2) | 10 (71.4) | 37 (100) | ||
| Imaging finding | None | 18 (35.3) | 6 (42.9) | 12 (32.4) | 0.005 |
| Small intestinal tumor | 22 (43.1) | 3 (21.4) | 19 (51.4) | ||
| Wall thickening | 7 (13.7) | 1 (7.1) | 6 (16.2) | ||
| Not performed | 4 (7.8) | 4 (28.6) | 0 (0.0) | ||
| Presentation | None | 1 (2.0) | 0 (0) | 1 (2.8) | 0.501 |
| Abdominal pain | 12 (23.5) | 5 (35.7) | 7 (19.4) | ||
| GI bleeding | 29 (56.9) | 6 (42.9) | 22 (61.1) | ||
| Other | 9 (17.6) | 3 (21.4) | 6 (16.7) | ||
| Location | Duodenum | 11 (21.7) | 2 (14.3) | 9 (24.3) | 0.615 |
| Jejunum | 19 (37.3) | 5 (35.7) | 14 (37.8) | ||
| Ileum | 21 (41.2) | 7 (50) | 14 (37.8) |
Table 2 Survival and mortality rate associated with benign and malignant lesions (n = 51)
| n (%) | Died | Survived | P value | |||
| Malignant tumors (n = 37) | GIST (n = 14) | Gastrointestinal stromal tumor | 14 (27.5) | 0 (0.0) | 14 (100.0) | 0.015a |
| Non-GIST (n = 23) | Adenocarcinoma | 9 (17.6) | 4 (44.4) | 5 (55.6) | ||
| Lymphoma | 8 (15.7) | 2 (25.0) | 6 (75.0) | |||
| Neuroendocrine tumor | 2 (3.9) | 0 (0.0) | 2 (0.0) | |||
| Sarcomatoid carcinoma | 2 (3.9) | 1 (50.0) | 1 (50.0) | |||
| Metastatic tumors1 | 2 (3.9) | 1 (50.0) | 1 (50.0) | |||
| Benign tumors (n = 14) | 14 (25.5) | 0 (0.0) | 14 (100.0) |
Table 3 Outcomes and management of malignant small bowel tumors (n = 37)
| Diagnosis | n (%) | Outcome (n) | Management (n) |
| Malignant small bowel tumors | |||
| GIST | 14 (37.8) | Cure (14) | Operation (13) and Target therapy (1) |
| Adenocarcinoma | 9 (24.3) | Cure (6) Expire (4) | Operation (4) Chemotherapy (2) Operation and chemotherapy (3) Hospice care (1) |
| Lymphoma | 8 (21.6) | Cure (6) Expire (2) | Chemotherapy (7) Operation and chemotherapy (1) |
| Sarcomatoid carcinoma | 2 (5.4) | Expire (1) Lost to follow-up (1) | Operation (1) |
| Neuroendocrine tumor | 2 (5.4) | Cure (2) | Operation (2) |
| Metastatic squamous cell carcinoma | 1 (2.7) | Expire (1) | Operation (1) |
| Metastatic pancreatic cancer | 1 (2.7) | Follow-up (1) | Operation and chemotherapy (1) |
| Benign small bowel tumors | |||
| Hyperplastic polyp | 3 (21.4) | Follow-up (4) | Biopsy (3) |
| Lipoma | 3 (21.4) | Follow-up (3) | Unroofing polypectomy (1) Biopsy (2) |
| Peutz-Jeghers syndrome | 2 (14.3) | Follow-up (2) | Polypectomy (2) |
| Adenoma | 2 (14.3) | Cure (2) | Operation (1) Polypectomy (1) |
| Lymphatic hyperplasia | 1 (7.1) | Follow-up (1) | Biopsy (1) |
| Ectopic gastric mucosa | 1 (7.1) | Follow-up (1) | Biopsy (1) |
| Ectopic pancreas | 1 (7.1) | Cure (1) | Operation (1) |
| Inflammatory myofibroblast tumor | 1 (7.1) | Cure (1) | Operation (1) |
- Citation: Liu FC, Wang CH, Chen PJ, Shih YL, Lin HH, Lin JC, Chang WK, Hsieh TY, Lin GM, Huang TY. Characteristics and prognosis of small bowel tumors: A retrospective study. World J Clin Cases 2024; 12(34): 6696-6704
- URL: https://www.wjgnet.com/2307-8960/full/v12/i34/6696.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v12.i34.6696