Copyright
©The Author(s) 2024.
World J Clin Cases. Sep 16, 2024; 12(26): 5854-5858
Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5854
Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5854
Group in PAX family | Member in PAX family | Expression site during embryogenesis | Involvement in tumorigenicity |
I | PAX1 | Skeleton, thymus, pharyngeal pouch | |
PAX9 | Skeleton, teeth, thymus | ||
PAX2 | Kidney, CNS | Bladder and renal cancers | |
II | PAX5 | B cells, CNS | Lymphomas |
PAX8 | Kidneys, thyroid gland, CNS | Thyroid, ovarian, and cervical cancers | |
III | PAX3 | Neural crest, CNS, muscle | Melanoma, rhabdomyosarcoma |
PAX7 | Same as above | Rhabdomyosarcoma | |
IV | PAX4 | Pancreas, gut | |
PAX5 | Pancreas, gut, and eyes | Gastrointestinal cancers |
- Citation: Zhou JH, Zhang XN. Paired box proteins as diagnostic biomarkers for endocervical adenocarcinoma. World J Clin Cases 2024; 12(26): 5854-5858
- URL: https://www.wjgnet.com/2307-8960/full/v12/i26/5854.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v12.i26.5854