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©The Author(s) 2024.
World J Clin Cases. Sep 6, 2024; 12(25): 5681-5696
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5681
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5681
General clinical data | Sepsis group (T) | Control group (C) | T value | P value |
Number of cases | 10 | 10 | ||
Age (years) | 83.10 ± 10.05 | 81.80 ± 9.39 | 0.334 | |
Height (cm) | 163 ± 7.2 | 165.7 ± 9.07 | 0.4703 | |
Weight (kg) | 60.4 ± 8.45 | 66.4 ± 12.5 | 0.2247 | |
Systolic blood pressure (kPa) | 15.95 ± 2.2 | 19.64 ± 2.23 | 0.0016 | b |
Diastolic pressure (kPa) | 9.93 ± 1.44 | 10.55 ± 1.76 | 0.4046 | |
White blood cell count (109/L) | 15.1 ± 7.57 | 6.15 ± 1.44 | 0.0017 | b |
Neutrophil percentage (%) | 88.11 ± 5.47 | 62.46 ± 5.99 | < 0.0001 | d |
Platelet count (1012/L) | 162.3 ± 88.28 | 208.1 ± 41.68 | 0.1552 | |
Alanine aminotransferase (U/L) | 100.94 ± 157.5 | 17.51 ± 7.77 | 0.1116 | b |
Total bilirubin (μmol/L) | 24.08 ± 23.58 | 14.85 ± 7.23 | 0.2521 | |
Creatinine (μmol/L) | 130.44 ± 76.68 | 70.84 ± 13.26 | 0.0262 | a |
C-reactive protein (mg/L) | 141 ± 63.09 | 1.54 ± 1.15 | < 0.0001 | d |
Procalcitonin (ng/mL) | 14.51 ± 16.96 | 0.04 ± 0.01 | 0.0147 | a |
D-dimer (ng/mL) | 12.88 ± 27.55 | 0.55 ± 0.55 | 0.1742 | a |
No. | Cytokine | Sepsis group (T) | Control group (C) | T value | P value |
1 | 6Ckine_CCL21 | 22115.55 ± 5190.13 | 19744.73 ± 3054.24 | 0.26 | |
2 | BCA-1_CXCL13 | 69.83 ± 23.97 | 73.73 ± 130.56 | 0.93 | |
3 | CTACK_CCL27 | 779.84 ± 438.20 | 529.79 ± 199.55 | 0.14 | |
4 | ENa-78_CXCL5 | 2999.36 ± 3172.84 | 939.51 ± 182.15 | 0.08 | |
5 | EOtaxin-2_CCL24 | 29.51 ± 13.71 | 45.68 ± 20.90 | 0.07 | |
6 | EOtaxin-3_CCL26 | 104.94 ± 53.77 | 78.45 ± 16.06 | 0.19 | |
7 | Eotaxin_CCL11 | 76.63 ± 38.25 | 83.49 ± 33.94 | 0.69 | |
8 | Fractalkine_CX3CL1 | 302.24 ± 163.08 | 118.26 ± 36.84 | 0.01 | a |
9 | GCP-2_CXCL6 | 54.87 ± 39.74 | 36.08 ± 19.61 | 0.23 | |
10 | GM-CSF | 27.55 ± 10.48 | 18.01 ± 4.52 | 0.03 | a |
11 | Gro minus a_CXCL1 | 396.70 ± 471.60 | 217.92 ± 29.77 | 0.29 | |
12 | Gro-b_CXCL2 | 79.72 ± 52.39 | 116.70 ± 76.76 | 0.25 | |
13 | I-309_Ccl1 | 68.07 ± 22.17 | 51.49 ± 8.77 | 0.06 | |
14 | I-TAC_CXCL11 | 98.14 ± 95.41 | 63.55 ± 17.94 | 0.31 | |
15 | IFN-g | 64.52 ± 73.72 | 20.94 ± 6.25 | 0.11 | |
16 | IL-10 | 84.44 ± 192.83 | 6.03 ± 1.30 | 0.25 | |
17 | IL-16 | 315.86 ± 100.55 | 179.71 ± 64.95 | 0.00 | c |
18 | IL-1B | 5.53 ± 3.89 | 2.81 ± 0.55 | 0.07 | |
19 | IL-2 | 16.03 ± 25.31 | 6.37 ± 7.86 | 0.23 | |
20 | IL-4 | 56.53 ± 18.81 | 53.53 ± 19.02 | 0.74 | |
21 | IL-6 | 3575.78 ± 7581.85 | 14.27 ± 15.51 | 0.19 | |
22 | IL-8_CXCL8 | 704.18 ± 1779.37 | 13.77 ± 12.44 | 0.27 | |
23 | IP-10_CXcl10 | 488.38 ± 687.30 | 120.44 ± 50.64 | 0.14 | |
24 | McP-1_CCL2 | 342.19 ± 565.76 | 60.92 ± 13.31 | 0.17 | |
25 | McP-2_CCL8 | 20.41 ± 14.52 | 12.89 ± 6.68 | 0.18 | |
26 | McP-3_CCL7 | 181.11 ± 91.81 | 139.20 ± 68.38 | 0.29 | |
27 | McP-4_CCL13 | 51.51 ± 54.87 | 45.39 ± 15.85 | 0.75 | |
28 | MDC_CL22 | 205.13 ± 104.45 | 252.88 ± 157.92 | 0.46 | |
29 | MIF | 4255.04 ± 3872.22 | 4984.17 ± 2222.53 | 0.63 | |
30 | MIG_CXCL9 | 475.39 ± 420.47 | 96.37 ± 68.50 | 0.02 | a |
31 | MIP-1a_CL3 | 35.18 ± 41.11 | 8.40 ± 3.46 | 0.08 | |
32 | MIP-1delta_CCL15 | 2399.60 ± 816.60 | 1986.99 ± 836.93 | 0.30 | |
33 | MIP-3A_CCL20 | 245.17 ± 606.30 | 6.20 ± 3.72 | 0.27 | |
34 | MIP-3b_CCL19 | 411.58 ± 234.76 | 244.49 ± 92.84 | 0.07 | |
35 | MpIF-1 CCL23 | 748.86 ± 663.34 | 161.30 ± 70.52 | 0.03 | a |
36 | SCYB16_CXCL16 | 594.64 ± 146.81 | 345.80 ± 198.26 | 0.01 | b |
37 | Sdf-1a +b_CXCL12 | 2201.58 ± 418.86 | 1853.09 ± 765.81 | 0.25 | |
38 | Tarc CL17 | 12.65 ± 14.57 | 21.31 ± 28.89 | 0.43 | |
39 | TECK_CCL25 | 1541.17 ± 697.26 | 931.70 ± 204.77 | 0.03 | a |
40 | TNF-α | 222.08 ± 272.34 | 71.74 ± 21.85 | 0.13 |
- Citation: Liu HX, Wang YY, Yang XF. Differential expression of plasma cytokines in sepsis patients and their clinical implications. World J Clin Cases 2024; 12(25): 5681-5696
- URL: https://www.wjgnet.com/2307-8960/full/v12/i25/5681.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v12.i25.5681