Cheesy material on macroscopic on-site evaluation after endoscopic ultrasound-guided fine-needle biopsy: Don't miss the tuberculosis

Table 1 Clinical presentation and endoscopic ultrasound finding of pancreatic tuberculosis patients

Ref.	No. of patients	Age	Sex	Clinical presentation	EUS finding	Microbiological and histological findings
Diaconu et al[5], 2022	1	55	F	Fever, jaundice, and asthenia	Cephalic pancreatic lesion with changes suggestive of chronic pancreatitis	Positive culture
Miyamoto et al[7], 2022	1	19	F	Abdominal pain and weight loss		Positive PCR for MT, granulomas with caseous necrosis and acid-fast bacilli
Hoilat et al[8], 2020	1	26	M	Abdominal pain, increased nausea and vomiting	Hypoechoic lesion	FNA: Abundant fibrinopurulent exudate and necrotizing suppurative granulomatous inflammation
Ray et al[9], 2021	16	13-59	12 M, 4 F	Epigastric pain, weight loss, anorexia, fever, and jaundice		5 EUS-FNA; 5 CT-FNA; 6 Surgery
Chang-Xin et al[10], 2022	1	24	F	Jaundice		Granulomatous inflammation infiltrated by multinucleated giant cells in FNA; Positive tuberculin skin test and tuberculous infection of T cells spot test

CT: Computed tomography, MT: Mycobacterium tuberculosis, FNA: Fine needle aspiration; PCR: Polymerase chain reaction.

Table 2 Macroscopic on-site evaluation score and sample classification[24]

Score	Aspects of the core	Classification of the biopsy
0	No material	Negative
1	Haematic or necrotic material	Acceptable
2	≥ 1 core tissue with ≤ 2 mm yellowish-white	Positive
3	≥ 1 core tissue with > 2 mm yellowish-white	Positive

Table 3 Sites of tuberculosis with cheesy material

Ref.	No. of patients	Presentation	Site of tuberculosis	Procedure
Yeat et al[26]	1	Pontomedullary junction, ring-enhancing lobulated lesion	Brainstem	Suboccipital craniotomy
Gopakumar et al[27]	1	Retropharyngeal cold abscess	Cervical lymphadenitis	Surgical exploration of the parapharyngeal space by needle aspiration
Ng et al[28]	1	Right adnexal mass	Abdominopelvic	Exploratory laparotomy
Lakhey et al[29]	122		Lymphadenopathy	Fine-needle aspiration cytology
Sahoo et al[30]	1	Pain in the left foot	Talus bone	Debridement and curettage of the lesion

Table 4 Doses of antitubercular therapy

Drugs	Doses (mg/kg/d)	Duration (mo)
Rifampin	10 (8-12)	6
Isoniazid	5 (4-6)	6
Pyrazinamide	25 (20-30)	2
Ethambutol	15 (15-20)	2