Multiple skin abscesses associated with bacteremia caused by Burkholderia gladioli: A case report

Table 1 Results of four sensitivity tests by the Kirby-Bauer method

Diameter of inhibition zone (mm)	Abscess secretion culture (first)	Abscess secretion culture (second)	Aerobic blood culture (first)	Aerobic blood culture (second)
TMP-SMZ	36	36	30	26
Meropenem	28	27	22	25
Minocycline	26	27	22	26

TMP-SMZ: Trimethoprim-sulfamethoxazole.

Table 2 Summary of cases with abscesses caused by Burkholderia gladioli infections

Ref.	Age/gender	Basic diseases	Clinical features	Medical therapy	Outcome
Ross et al[2], 1995	34 yr/M	CGD	Facial abscess and left otitis externa abscess	TMP-SMZ and amoxicillin/clavulanate	Recovery
Hoare et al[3], 1996	5 yr/M	CGD	Necrotic abscess, bacteremia and multiple hemorrhages	TMP-SMZ, ciprofloxacin and gentamicin	Recovery
Boyanton et al[4], 2005	6 yr/M	CGD	Left fourth metatarsal bone abscess	Ciprofloxacin, intravenous ticarcillin/clavulanate and gentamicin	Recovery
Marom et al[5], 2018	13 mo/not given	CGD	Facial abscess	Cefazolin, clindamycin and cephalexin	Recovery
Khan et al[6], 1996	22 yr/M	CF	Chest wall abscess, empyema and bacteremia	Imipenem	Death
Jones et al[7], 2001	17 yr/M	CF	Recurrent abscess	Piperacillin, tazocin, TMP-SMZ, meropenem, imipenem, tobramycin and ceftazidime	Death
Brizendine et al[8], 2012	39 yr/M	CF	Lung abscess, bacteremia, necrotizing pneumonia and empyema	TMP-SMZ, piperacillin/tazobactam	Death
Church et al[9], 2009	41 yr/M	CF	Mediastinal abscess	TMP-SMZ, meropenem, and ceftazidime	Recovery
Kennedy et al[10], 2007	Not given	CF	Mediastinal abscess	Not given	Recovery
Waseem et al[11], 2008	17 yr/M	Type 1 diabetes	Right-sided waist abscess and diabetic ketoacidosis	Levofloxacin	Recovery
Choi et al[12], 2014	55 yr/F	No	Cystic neck abscess and silicone granulomas	Not given	Recovery
Present report: Wang YT, et al	74 yr/M	Pneumonia	Multiple skin abscesses and bacteremia	Cefoperazone, clarithromycin, doxycycline, meropenem, moxifloxacin, TMP-SMZ, and etilmicin	Recovery

M: Male; F: Female; CGD: Chronic granulomatous disease; CF: Cystic fibrosis.