Undifferentiated embryonal sarcoma of the liver: Clinical characteristics and outcomes

Figure 1 Computed tomography images of undifferentiated embryonal liver sarcoma. A: Plain CT scan revealed hepatomegaly. In the right lobe of the liver, there was a large oval cystic-solid mixed mass measruing 12.0 cm × 8.8 cm × 12.2 cm, with a clear boundary and non-homogeneous density; the solid part had multiple nodular soft tissue density shadows; B: In the arterial phase, the cystic components of the mass were not obviously strengthened; however, the solid components of the mass were obviously strengthened; C: In the portal venous phase, the enhanced extent of the masses was a little more obvious than that in the arterial phase; The enhancement of the masses was significantly lower than that of surrounding parenchyma; D: In the delayed phase, the enhanced extent of the masses was still a little more obvious than that in the arterial phase.

Figure 2 Pathological findings of undifferentiated embryonal liver sarcoma. A: Macroscopically, the large cystic mass with an amount of dark red blood clots in the lumen was observed; B: Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells, and mesenchymal hamartomalike lesions were partially seen (hematoxylin and eosin staining).

Figure 3 Immunohistochemical examinations of undifferentiated embryonal liver sarcoma. Immunohistochemical analysis showed that the tumor stained positively for α1-antitrypsin (+) (A), α-fetoprotein (-) (B), smooth muscle actin (-) (C), cytokeratin (-) (D), Desmin (-) (E), and Ki67 (F). (+): The test is positive; (-): The test is negative.