Unusual histological variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation

Figure 1 Photograph showing multiple neurofibromas, present all over the body.

Figure 2 Photomicrograph. A: Photomicrograph of cytological smear showing spindle cells with pleomorphic hyperchromatic nuclei and a plump cell (arrow) with abundant eosinophilic cytoplasm; B: Photomicrograph showing hypercellular areas (Antoni A) of spindle cells having hyperchromatic nuclei and hypocellular areas (Antoni B) (100 ×). Inset shows rhabdomyoblastic differentiation (400 ×).

Figure 3 Immunohistochemistry. A: Immunohistochemistry showing focal S100 positivity in spindle cells; B: Immunohistochemistry showing Desmin positivity in rhabdomyoblasts.