Primary renal lymphoma presenting as renal failure: A case report and review of literature from 1989

Figure 1 Histologic, immunohistochemical examination and electron-microscopic findings. A: Diffuse infiltration of pleomorphic cells is identified throughout the specimen (HE × 5) (× 2.0 k); B: The cells were immunoreactive for CD20 (× 20) (× 1.5 k); C: Negative for CD3 (× 20) (× 1.0 k); D and E: No electron-dense deposit is recognized, and glomerular basement membrane appeared normal in thickness, contour, and texture; however, strikingly, diffuse prominent infiltration of atypical lymphocytes is seen in the interstitium (× 2.0 k); F and G: The cells exhibited round to oval cleaved and non-cleaved nuclei with variable clumping of chromatin and large prominent marginated nucleoli.

Figure 2 Radiologic findings. A: Abdominal computed tomography (CT) examination revealed diffuse homogeneous enhancement in both kidneys without definite visible cortico-medullary differentiation and was diagnosed as lymphomatous involvement; B: On fluorodeoxyglucose-positron emission tomography CT, intense hypermetabolism was also identified in both kidneys.