Anti-phospholipase A2 receptor-associated membranous nephropathy with human immunodeficiency virus infection treated with telitacicept: A case report

Figure 1 Biopsy findings in patients with human immunodeficiency virus infection and membranous nephropathy. A: Histological analysis of biopsy tissues via light microscopy showed eosinophilic deposits under the epithelium and a thickening of the basement membrane with vacuoles and granules visualized by periodic acid-Schiff staining (× 400); B: Periodic acid methenamine silver staining visualization also highlights vacuoles and granules (× 400); C: Immunofluorescent evaluation of renal tissues (× 400) showed granular phospholipase A2 receptor-associated deposition along capillary loops; D: Electron microscopy showed subepithelial electron-dense deposits with the associated basement membrane, consistent with stage I-II membranous nephropathy (× 8000).

Figure 2 Patient’s clinical course. TAC: Tacrolimus