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©The Author(s) 2022.
World J Clin Cases. May 26, 2022; 10(15): 4971-4984
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4971
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4971
Figure 1 Magnetic resonance imaging and retroperitoneal B-ultrasound manifestations.
A: Thickened small bowel wall and whole colon, with enlarged regional lymph nodes at the mesenteries; B: Retroperitoneal B-ultrasound manifestation: Multiple retroperitoneal lymph nodes are enlarged. The orange arrow points to the largest swollen lymph node; C: Pathological results of lymph node puncture showing the destruction of lymph node structure and diffuse proliferation and infiltration of tumor cells in the paracortical area and medullary sinus.
Figure 2 Endoscopic and pathologic findings of the stomach and intestines.
A: Colonoscopy manifestation: multiple ulcers are seen in the distal ileum, colon and rectum, with two large ulcerations each in the distal ileum and sigmoid colon (Orange arrow); B: Gastroscopy shows chronic atrophic gastritis.
Figure 3 Superior mesenteric arteriography and perioperative images.
A: Superior mesenteric arteriography shows rupture and hemorrhage of a straight arteriole distal to the ileocolic artery; subsequently, microspring coils are used to embolize the diseased vessels, and repeated angiography shows that the hemorrhagic lesion disappears 5 minutes later (Red box); B: A large amount of yellow-green intestinal fluid in the abdominal cavity and ileum perforation are observed during the operation (Orange arrow).
Figure 4 Immunohistochemical findings.
Colonic lymphoid cells undergo immunophenotyping by immunohistochemistry. Lymphoid cells show positivity for CD3, CD5, CD7 and CD8, and negativity for CD4, CD20 and CD56. The Ki-67 proliferative index is low (< 10%). Monoclonal gene rearrangement is determined in T-cell receptor-clonality assay by polymerase chain reaction.
Figure 5 TCRβ/γ clonal gene rearrangement.
TCRβ/γ clonal gene rearrangement test by PCR and Capillary Electrophoresis. The results shows positivity for C511-BA, C511-BB, and negativity for C511-GA, C511-BC and C511-GB and C511-D.
- Citation: Weng CY, Ye C, Fan YH, Lv B, Zhang CL, Li M. CD8-positive indolent T-Cell lymphoproliferative disorder of the gastrointestinal tract: A case report and review of literature. World J Clin Cases 2022; 10(15): 4971-4984
- URL: https://www.wjgnet.com/2307-8960/full/v10/i15/4971.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i15.4971