Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2021; 9(31): 9571-9576
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9571
Acute esophageal necrosis as a complication of diabetic ketoacidosis: A case report
Kasey Moss, Tahrin Mahmood, Robert Spaziani
Kasey Moss, Department of Internal Medicine, McMaster University, Hamilton L8S 4L8, Ontario, Canada
Tahrin Mahmood, Robert Spaziani, Division of Gastroenterology, McMaster University, Hamilton L8S 4L8, Ontario, Canada
Author contributions: Moss K was the primary author who wrote and revised the paper; Mahmood T contributed to the writing and revising process heavily; Spaziani R provided his expertise and assistance in editing the paper and was the primary physician involved in the patient encounter; all authors have read and approve the final manuscript.
Informed consent statement: The patient whom the case report was written about provided verbal consent to have their case written and submitted for publication prior to the commencement of the case report being written.
Conflict-of-interest statement: None of the authors has any conflicts of interest.
CARE Checklist (2016) statement: The authors have submitted and followed the guidelines within the CARE checklist (2016) statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Robert Spaziani, FRCP (C), Attending Doctor, Department of Internal Medicine, Division of Gastroenterology, McMaster University, 1280 Main Street West, Hamilton L8S 4L8, Ontario, Canada. spaziar@mcmaster.ca
Received: March 27, 2021
Peer-review started: March 27, 2021
First decision: June 3, 2021
Revised: June 18, 2021
Accepted: September 22, 2021
Article in press: September 22, 2021
Published online: November 6, 2021
Processing time: 215 Days and 16 Hours
Core Tip

Core Tip: Acute esophageal necrosis (AEN) is a rare condition with a mortality rate greater than 30%. It has been linked to low volume states including diabetic ketoacidosis in case reports but is usually associated with overt gastrointestinal bleeding (GIB). This report provides an important description of a patient presenting with AEN and no overt GIB. Interestingly, the apparent trigger for ketoacidosis appears to be a ketogenic diet. The case explores Glucagon-like peptide-1 receptor agonists as a possible AEN precipitant, which is not a finding previously described in the existing literature.