Retrospective Cohort Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2021; 9(31): 9395-9405
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9395
Extrapancreatic necrosis volume: A new tool in acute pancreatitis severity assessment?
Bogdan Cucuteanu, Dragoş Negru, Otilia Gavrilescu, Iolanda Valentina Popa, Mariana Floria, Cătălina Mihai, Cristina Cijevschi Prelipcean, Mihaela Dranga
Bogdan Cucuteanu, Dragoş Negru, Department of Radiology, “Grigore T. Popa” University of Medicine and Pharmacy, “Saint Spiridon” Hospital, Iaşi City 700115, Romania
Otilia Gavrilescu, Cătălina Mihai, Cristina Cijevschi Prelipcean, Mihaela Dranga, Department of Gastroenterology, “Grigore T. Popa” University of Medicine and Pharmacy, “Saint Spiridon” Hospital, Iaşi City 700115, Romania
Iolanda Valentina Popa, Department of Gastroenterology, “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi City 700115, Romania
Mariana Floria, Department of Internal Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi City 700115, Romania
Author contributions: Dranga M and Cucuteanu B designed and performed the research, and wrote the paper; Dranga M, Popa IV, and Mihai C designed the research, supervised the report, and contributed to the analysis; Gavrilescu O, Floria M, and Mihai C provided clinical advice; Cijevschi Prelipcean C, Negru D, and Mihai C supervised the report.
Institutional review board statement: This study was approved by the Ethics Committee of the “Grigore T. Popa” University of Medicine and Pharmacy, Iaşi City, Romania (No. 65/6.04.2021).
Informed consent statement: All of the patients were informed about the study and provided signed informed consent.
Conflict-of-interest statement: The authors declare that they have no conflicting interests to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cătălina Mihai, MD, PhD, Associate Professor, Department of Gastroenterology, “Grigore T. Popa” University of Medicine and Pharmacy, “Saint Spiridon” Hospital, S University Street 16, Iaşi City 700115, Romania. catalinamihai@yahoo.com
Received: April 7, 2021
Peer-review started: April 7, 2021
First decision: June 27, 2021
Revised: July 16, 2021
Accepted: September 3, 2021
Article in press: September 3, 2021
Published online: November 6, 2021
Processing time: 204 Days and 19.9 Hours
Core Tip

Core Tip: This retrospective study evaluated the role of extrapancreatic necrosis volume in the evaluation of acute pancreatitis. The patients were evaluated by established computed tomography scores, the computed tomography severity index (CTSI), and the modified CTSI, as well as a new method using the extrapancreatic necrosis volume. Although all the imaging scores had a strong correlation with the severity of acute pancreatitis, the extrapancreatic necrosis volume had the best diagnostic accuracy for the severe form.