Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4116
Peer-review started: January 25, 2021
First decision: March 25, 2021
Revised: April 4, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: June 16, 2021
Processing time: 121 Days and 3 Hours
Core Tip: Traditional cold therapy (e.g., topically icing the injured area) may not be helpful but rather act as a barrier to recovery process. A prolonged period of cold on the skin was reported to lead to a reduction of the blood flow, resulting in tissue death or even permanent nerve damage. Hyperbaric gaseous cryotherapy, also known as neurocryostimulation, has shown the ability to induce greater analgesic, anti-inflammatory, vasomotor, and muscle relaxing effects than other traditional cold application, thus quickening recovery and heal following soft tissue injuries. More high quality level evidence is still needed to confirm the efficacy of hyperbaric gaseous cryotherapy about its clinical effects for soft-tissue injuries in the future, in order to find the optimal way to use it.
