Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2021; 9(10): 2274-2280
Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2274
Bilateral retrocorneal hyaline scrolls secondary to asymptomatic congenital syphilis: A case report
Yu-Qi Jin, Yong-Ping Hu, Qi Dai, Shuang-Qing Wu
Yu-Qi Jin, Yong-Ping Hu, Department of Ophthalmology, Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Qi Dai, The Center of Cornea and Refraction, The Eye Hospital of Wenzhou Medical University, Hangzhou 325027, Zhejiang Province, China
Shuang-Qing Wu, Department of Ophthalmology, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital, Hangzhou 310003, Zhejiang Province, China
Author contributions: Hu YP contributed to case conceptualization; Dai Q contributed to data curation; Jin YQ contributed to funding acquisition; Wu SQ contributed to supervision; Jin YQ wrote the original draft; Wu SQ contributed to manuscript review and editing.
Supported by Zhejiang Provincial Medical and Health Technology Project, No. 2020KY215.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article are reported.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shuang-Qing Wu, MD, PhD, Chief Doctor, Department of Ophthalmology, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital, No. 208 Huancheng Road East, Hangzhou 310003, Zhejiang Province, China. shuangqingwu@zju.edu.cn
Received: September 14, 2020
Peer-review started: September 14, 2020
First decision: December 14, 2020
Revised: December 16, 2020
Accepted: January 27, 2021
Article in press: January 27, 2021
Published online: April 6, 2021
Processing time: 196 Days and 23.4 Hours
Core Tip

Core Tip: Retrocorneal scrolls are usually considered to be associated with some infectious keratitis. Here, we report a case of bilateral retrocorneal hyaline scrolls and corneal gutta, without other ocular or systemic positive signs, which was likely induced by asymptomatic congenital syphilis. The characteristic changes of the cornea were observed by in vivo confocal microscopy. The removed scrolls were analyzed by hematoxylin-eosin staining and scanning electron microscopy. Our findings provide new insight into the pathogenesis of keratopathy in congenital syphilitic corneal disease.