Zhang MY, Min CC, Fu WW, Liu H, Yin XY, Zhang CP, Tian ZB, Li XY. Early colon cancer with enteropathy-associated T-cell lymphoma involving the whole gastrointestinal tract: A case report. World J Clin Cases 2020; 8(22): 5781-5789 [PMID: 33344574 DOI: 10.12998/wjcc.v8.i22.5781]
Corresponding Author of This Article
Xiao-Yu Li, MD, Associate Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. lixiaoyu05@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Meng-Yuan Zhang, Cong-Cong Min, Hua Liu, Xiao-Yan Yin, Cui-Ping Zhang, Zi-Bin Tian, Xiao-Yu Li, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Wei-Wei Fu, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Author contributions: Zhang MY and Min CC collected the clinical data and wrote the manuscript; Fu WW provided pathological pictures and contributed to pathological diagnosis; Liu H, Yin XY, and Zhang CP contributed to clinical data collection and follow-up; Tian ZB directed the study and reviewed the final manuscript; Li XY performed the endoscopic resection for the patient and revised the article.
Supported byNational Natural Science Foundation of China, No. 81802777; Shandong Higher Education Research Center Scientific Research Project, No. YJKT201953; Shandong Province 2018 Professional Degree Postgraduate Teaching Case Library Project, No. SDYAL18049; Shandong Province 2018 Postgraduate Mentoring Ability Improvement Project, No. SDYY18073; and the "Clinical Medicine + X" Project of Qingdao University Hospital.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Yu Li, MD, Associate Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. lixiaoyu05@163.com
Received: August 13, 2020 Peer-review started: August 13, 2020 First decision: August 21, 2020 Revised: August 28, 2020 Accepted: September 11, 2020 Article in press: September 11, 2020 Published online: November 26, 2020 Processing time: 103 Days and 15.2 Hours
Core Tip
Core Tip: Enteropathy-associated T-cell lymphoma (EATL) is a rare aggressive lymphoma of the gastrointestinal tract. We present the case of a male patient with chronic diarrhea for more than 5 mo, and colonoscopy showed multiple polyps with the pathology of early colonic cancer. Endoscopic mucosal resection was performed. Postoperative histopathological and immunohistochemistry results suggested EATL with moderately differentiated adenocarcinoma confined to the mucosa. This is a rare case of EATL involving the whole colon, duodenum, and small intestine, complicated with early colon cancer. Nonspecific clinical symptoms and typical endoscopy appearance pose difficulty in making an accurate diagnosis. More attention should be paid to the swollen colonic mucosa with a granular appearance in unexplained chronic diarrhea to avoid misdiagnosis.
