Liver injury in COVID-19: A minireview

doi:10.12998/wjcc.v8.i19.4303

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 8, Issue 19

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (11201)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-1) series.

Item

Count

PDF

576

WORD

222

HTML

4850

Figures (1-1)

509

Tables (1-1)

566

Sum=6723

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

557

Download

1214

Sum=1771

Publishing Process of This Article

Item

Count

Browse

798

Download

1909

Sum=2707

Oct 6, 2020 (publication date) through Mar 1, 2026

Times Cited of This Article

Times Cited (19)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Clin Cases. Oct 6, 2020; 8(19): 4303-4310
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4303

Liver injury in COVID-19: A minireview

Jian-Nan Zhao, Ying Fan, Shuo-Dong Wu

Jian-Nan Zhao, Ying Fan, Shuo-Dong Wu, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China

Author contributions: Zhao JN drafted and revised the manuscript; Fan Y and Wu SD reviewed and revised the manuscript; All authors read and approved the final version of the manuscript.

Conflict-of-interest statement: Authors declare no conflict of interests for this article.

Corresponding author: Ying Fan, MD, PhD, Doctor, Professor, Department of General Surgery, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. coolingpine78@163.com

Received: April 30, 2020
Peer-review started: April 30, 2020
First decision: May 21, 2020
Revised: June 1, 2020
Accepted: September 8, 2020
Article in press: September 8, 2020
Published online: October 6, 2020
Processing time: 150 Days and 17.5 Hours

Core Tip

Core Tip: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2. Liver injury was observed in COVID-19 patients especially in severe and critical types. Liver injury presented differentially based on disease severity, geographical areas, and patient age. It may be related to systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases. Special treatment is unnecessary in most mild liver injury cases and only one or two types of hepatoprotective drugs should be used to treat significant liver injury. Monitoring liver function is important parameter during the treatment of COVID-19 as it affects survival and recovery of patients, and its significance should be emphasized for doctors treating the disease.