Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2020; 8(11): 2339-2344
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2339
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2339
Macrophage activation syndrome as a complication of dermatomyositis: A case report
Ding-Xian Zhu, Jian-Jun Qiao, Hong Fang, Department of Dermatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Fang H designed the report; Qiao JJ collected the patient’s clinical data; Zhu DX analyzed the data and wrote the paper; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hong Fang, MD, Academic Fellow, Associate Specialist, Chief Doctor, Senior Consultant Dermatologist, Department of Dermatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. fanghongzy@zju.edu.cn
Received: March 9, 2020
Peer-review started: March 9, 2020
First decision: April 1, 2020
Revised: April 14, 2020
Accepted: April 29, 2020
Article in press: April 29, 2020
Published online: June 6, 2020
Processing time: 90 Days and 18.1 Hours
Peer-review started: March 9, 2020
First decision: April 1, 2020
Revised: April 14, 2020
Accepted: April 29, 2020
Article in press: April 29, 2020
Published online: June 6, 2020
Processing time: 90 Days and 18.1 Hours
Core Tip
Core tip: Macrophage activation syndrome is a potentially life-threatening complication of rheumatic disorders that occurs most commonly in patients with systemic juvenile idiopathic arthritis, systemic lupus erythematosus or adult-onset Still’s disease. It has rarely been reported in patients with dermatomyositis. Here, we describe a typical case of macrophage activation syndrome that developed in a 44-year-old woman with dermatomyositis, who presented with high serum ferritin level, cytopenia, liver dysfunction and central nervous system symptoms. This report was written to increase awareness of this life-threatening condition associated with dermatomyositis.