Case Control Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2020; 8(11): 2150-2161
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2150
Determination of vitamin D and analysis of risk factors for osteoporosis in patients with chronic pain
Bao-Lin Duan, Yuan-Rong Mao, Li-Qi Xue, Qing-Yuan Yu, Mei-Yi Liu
Bao-Lin Duan, Yuan-Rong Mao, Li-Qi Xue, Qing-Yuan Yu, Mei-Yi Liu, Department of Pain, Qinghai Provincial People’s Hospital, Xining 810000, Qinghai Province, China
Author contributions: Duan BL performed the majority of experiments and wrote the manuscript; Liu MY designed the study and corrected the manuscript; Mao YR was involved in analytical tools; Xue LQ and Yu QY participated in the collection of data.
Supported by the 2016 Guidance Project of Qinghai Provincial Health and Family Planning Commission, No. 2016-wjzdx-14.
Institutional review board statement: The study was approved by the ethics committee of Qinghai Provincial People’s Hospital.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at 1461519537@qq.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mei-Yi Liu, MD, Doctor, Department of Pain, Qinghai Provincial People’s Hospital, 2 Gonghe Road Chengdong District, Xining 810000, Qinghai Province, China. 1461519537@qq.com
Received: January 2, 2020
Peer-review started: January 2, 2020
First decision: February 26, 2020
Revised: April 17, 2020
Accepted: May 1, 2020
Article in press: May 1, 2020
Published online: June 6, 2020
Processing time: 157 Days and 10.8 Hours
Core Tip

Core tip: Vitamin D deficiency is common in chronic pain patients and healthy people, and its level is not different between the two, but severe deficiency is more common in patients with chronic pain. Vitamin D is not a risk factor for bone loss and osteoporosis. Age, parathyroid hormone, and calcium are risk factors for bone loss. Age, ethnicity, and altitude are risk factors for osteoporosis.