Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2019; 7(22): 3792-3799
Published online Nov 26, 2019. doi: 10.12998/wjcc.v7.i22.3792
Sagliker syndrome: A case report of a rare manifestation of uncontrolled secondary hyperparathyroidism in chronic renal failure
Yu Yu, Chen-Fang Zhu, Xiao Fu, Hua Xu
Yu Yu, Chen-Fang Zhu, Xiao Fu, Hua Xu, Department of General Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Discipline Construction Research Center of China Hospital Development Institute, Shanghai Jiao Tong University, Shanghai 200011, China
Author contributions: Yu Y collected the data and wrote the paper; Zhu CF was directly responsible for performing the operation and revised the paper; Fu X and Xu H designed the report and analyzed the data; all authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient herself for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Chen-Fang Zhu, MD, PhD, Department of General Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Discipline Construction Research Center of China Hospital Development Institute, Shanghai Jiao Tong University, Shanghai 200011, China. sammizz1977@126.com
Telephone: +86-13917603720
Received: June 12, 2019
Peer-review started: June 19, 2019
First decision: September 9, 2019
Revised: October 3, 2019
Accepted: October 15, 2019
Article in press: October 15, 2019
Published online: November 26, 2019
Processing time: 167 Days and 3.1 Hours
Core Tip

Core tip: This article reports one case of Sagliker syndrome, a rare complication of secondary hyperparathyroidism, which is characterized by disfiguring facial deformity, resulting in a lion-like face. We review the whole process of diagnosis and treatment in order to bring inspiration to other patients. Related articles are reviewed, and we make reasonable speculation of its risk factors. We also creatively put forward the hypothesis of its manifestation mechanisms and discuss its treatment modalities.